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Makale Tam Makale Uluslararası 2021 Açık erişimli

Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties

Duygu Köse, Harun Ün, Rüstem Anıl Uğan, Zekai Halıcı, Elif Çadırcı, Tuğba Bal, Aysenur Kahramanlar

Journal of Pharmacy and Pharmacology Cilt 73 · Sayı 10 · ss. 1302–1309 · 01.10.2021
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Özet

Objectives: We investigated, the effects of aprepitant (APRE) on the lung tissues of rats with an experimental polymicrobial sepsis model (CLP: cecal ligation and puncture) biochemically, molecularly and histopathologically.

Anahtar kelimeler

oxidative stress Activation INHIBITION SEPSIS rats nuclear factor kappa-B liver polymicrobial sepsis CECAL LIGATION Inflammatory cytokines Aprepitant tumour necrosis factor alpha NEUROKININ-1 RECEPTOR ANTAGONISTS ANIMAL-MODELS

Sürdürülebilir Kalkınma Amaçları

  • SKA 3: Sağlıklı Bireyler

Atıf için künye

Köse, D., Ün, H., Uğan, R. A., Halıcı, Z., Çadırcı, E., Bal, T., & Kahramanlar, A. (2021). Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties. Journal of Pharmacy and Pharmacology, 73(10), 1302–1309. https://doi.org/10.1093/jpp/rgab088

BibTeX 
@article{kose2021-24443,
  author = {Köse, Duygu and Ün, Harun and Uğan, Rüstem Anıl and Halıcı, Zekai and Çadırcı, Elif and Bal, Tuğba and Kahramanlar, Aysenur},
  title = {Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties},
  journal = {Journal of Pharmacy and Pharmacology},
  year = {2021},
  volume = {73},
  number = {10},
  pages = {1302--1309},
  issn = {0022-3573},
  doi = {10.1093/jpp/rgab088},
  url = {https://akademik.atauni.edu.tr/yayinlar/24443-aprepitant-an-antiemetic-drug-contributes-to-the-prevention-of-acute-lung-injury}
}