Do peripheral melatonin agonists improve bone fracture healing? The effects of agomelatine and ramelteon on experimental bone fracture
Özet
Melatonin improves fracture healing, but the long-term use of melatonin seems impracticable in the treatment of fracture due to side effects caused by hormonal stress on chronological rhythm. Ramelteon (RAMEL) and agomelatine (AGO) are non-selective peripheral melatonin receptor (MT) agonists. This study investigated the effects on bone fracture healing of these MT agonists, which do not affect the central nervous system.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Köse, D., Kose, A., Halıcı, Z., Gürbüz, M. A., Aydın, A., Uğan, R. A., Karaman, A., & Toktay, E. (2020). Do peripheral melatonin agonists improve bone fracture healing? The effects of agomelatine and ramelteon on experimental bone fracture. EUROPEAN JOURNAL OF PHARMACOLOGY, 887. https://doi.org/10.1016/j.ejphar.2020.173577
BibTeX
@article{kose2020-24442,
author = {Köse, Duygu and Kose, Ahmet and Halıcı, Zekai and Gürbüz, Muhammet Ali and Aydın, Ali and Uğan, Rüstem Anıl and Karaman, Adem and Toktay, Erdem},
title = {Do peripheral melatonin agonists improve bone fracture healing? The effects of agomelatine and ramelteon on experimental bone fracture},
journal = {EUROPEAN JOURNAL OF PHARMACOLOGY},
year = {2020},
volume = {887},
issn = {0014-2999},
doi = {10.1016/j.ejphar.2020.173577},
url = {https://akademik.atauni.edu.tr/yayinlar/24442-do-peripheral-melatonin-agonists-improve-bone-fracture-healing-the-effects-of}
}