Glycaemic control and complications in haemodialysis patients: The TURK-HEMODIAB Study
Özet
Background The most common cause of end-stage kidney disease is diabetes mellitus (DM). The most commonly used renal replacement therapy in Turkey and in many countries around the world is haemodialysis (HD). Glycaemia control is important in these populations. In this study we aimed to screen for glycaemic control and complications in a large population of diabetic HD patients in Turkey. Methods A total of 16 043 patients were screened in 253 dialysis centres in Turkey and 5038 diabetic HD patients were included in the study. At participating centres, patients' diabetes history, complications, medications, haemoglobin A1c (HbA1c) and other laboratory data were reviewed and recorded by nephrologists. Results The average age of the patients was 64.0 ± 11.2 years and 56% were male. The mean HbA1c was 7.4 ± 1.5%. Patients were divided into three groups according to the HbA1c level (<6.5%, 6.5-8% and >8%). As the HbA1c levels increased, the mean systolic blood pressure and diastolic blood pressure increased significantly. In addition, as the HbA1c levels increased, the number of patients with coronary artery disease, patients undergoing coronary artery bypass graft surgery and the rate of patients with diabetic retinopathy and vision loss increased. Diabetic foot disease and amputation rates were also higher in the group with poor glycaemic control. The number of patients using intensive or mixed insulin was also higher in the group with high HbA1c levels. In ordinal logistic regression analysis, age significantly decreased and higher body mass index slightly increased the risk of a higher HbA1c. Also, the need for a diabetic diet was greater in those with high HbA1c levels. Conclusion Our study highlights that the target values for diabetic HD patients in Turkey are partially compatible with the 2022 Kidney Disease: Improving Global Outcomes guidelines for diabetes management. Nevertheless, more effort and teamwork are needed to improve patient outcomes.
Anahtar kelimeler
Atıf için künye
Gungor, O., KORUCU, B., Oguz, E. G., EREN, N., KARACA URAL, Z., Dheir, H., Tatar, E., Inci, A., KOÇYİĞİT, İ., Aydin, Z., Ulutas, O., Kara, E., Altunoren, O., Yilmaz, Z., Sevinc, M., Sevinç, C., Surardamar, A., Islam, M., Akgol, C., … Arici, M. (2026). Glycaemic control and complications in haemodialysis patients: The TURK-HEMODIAB Study. Clinical Kidney Journal, 19(1). https://doi.org/10.1093/ckj/sfaf120
BibTeX
@article{gungor2026-243680,
author = {Gungor, Ozkan and KORUCU, BERFU and Oguz, Ebru Gok and EREN, NECMİ and KARACA URAL, Zeynep and Dheir, Hamad and Tatar, Erhan and Inci, Ayca and KOÇYİĞİT, İSMAİL and Aydin, Zeki and Ulutas, Ozkan and Kara, Ekrem and Altunoren, Orcun and Yilmaz, Zulfukar and Sevinc, Mustafa and Sevinç, Can and Surardamar, Atalay and Islam, Mahmud and Akgol, Cuneyt and Tonbul, Halil Zeki and Ozler, Tuba Elif and Guney, Ibrahim and Cevher, Simal Koksal and Uysal, Cihan and Guzel, Fatma Betul and Mutluay, Ruya and Ercan, Zafer and Sirali, Semahat Karahisar and Cankaya, Emre and Onan, Engin and Candan, Ferhan and Eroglu, Eray and Tezcan, Neslihan and Polat, Mehmet and Huzmeli, Can and Ozkurt, Sultan and Akagun, Tulin and Alp, Pinar and Ozelsancak, Ruya and Yurteri, Gurkan and Tanrisev, Mehmet and Ilter, Ali and Guvercin, Beyhan and Demir, Mehmet Emin and Tomar, Ozdem Kavraz and Azak, Alper and Turgut, Faruk Hilmi and Tuncay, Mehmet and Akdam, Hakan and Selen, Tamer and Yilmaz, Fatih and Danis, Ramazan and Eyupoglu, Sahin and Kumru, Gizem and Demir, Simge Bardak and Alagoz, Selma and Uzun, Sami and Ozdemir, Orhan and Adibelli, Zelal and Polat, Mehmet and Ulu, Ramazan and Murt, Ahmet and Dolarslan, Murside Esra and Bal, Ayse Zeynep and Ayar, Yavuz and Sensoy, Nazife Nur Ozer and Sezen, Mehmet and Sahutoglu, Tuncay and Kara, Ali Veysel and Turkmen, Ercan and Kayabasi, Hasan and Gorgulu, Numan and Hur, Ender and Yucel, Fatma Sibel Kocak and Eren, Zehra and Sahin, Garip and Kasapoglu, Umut and Biyik, Zeynep and Koyuncu, Sumeyra and Aydin, Mehmet Fetullah and Yildirim, Tolga and Kuzgun, Gulsah Sasak and Ustundag, Sedat and Celik, Abdulkadir and Akcali, Esra and Usalan, Ozlem and Kaya, Bulent and Altiparmak, Mehmet Riza and Tugcu, Murat and Olmaz, Refik and Erkus, Edip and Soypacaci, Zeki and Zorba, Belma Gokcen and Yavuz, Demet and Oztop, Kenan Evren and Ogutmen, Melike Betul and Harmankaya, Ozlem and Taymez, Dilek Guven and Kaptanogullari, Hakan and Magden, Kemal and Seyrek, Neslihan and Berktas, Haci Bayram and Erdem, Mehmet and Ozturk, Savas and Arikan, Izzet Hakki and Kutlay, Sim and Altun, Bulent and Ates, Kenan and Arici, Mustafa},
title = {Glycaemic control and complications in haemodialysis patients: The TURK-HEMODIAB Study},
journal = {Clinical Kidney Journal},
year = {2026},
volume = {19},
number = {1},
issn = {2048-8505},
doi = {10.1093/ckj/sfaf120},
url = {https://akademik.atauni.edu.tr/yayinlar/243680-glycaemic-control-and-complications-in-haemodialysis-patients-the-turk-hemodiab}
}