Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats
Özet
Background: Change in blood supply is held responsible for anesthesia-related abnormal tissue and organ perfusion. Decreased erythrocyte deformability and increased aggregation may be detected after surgery performed under general anesthesia. It was shown that nonsteroidal anti-inflammatory drugs decrease erythrocyte deformability. Lornoxicam and/or intravenous (iv) ibuprofen are commonly preferred analgesic agents for postoperative pain management. In this study, we aimed to investigate the effects of lornoxicam (2 mg/kg, iv) and ibuprofen (30 mg/kg, iv) on erythrocyte deformability, as well as hepatic and renal blood flows, in male rats.
Anahtar kelimeler
Atıf için künye
Arpaci, H., Comu, F. M., Kucuk, A., Kosem, B., Kartal, S., ŞIVGIN, V., Turgut, H. C., Aydın, M. E., Koc, D. S., & ARSLAN, M. (2016). Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats. Drug Design Development and Therapy, 10, 2477–2481. https://doi.org/10.2147/dddt.s113806
BibTeX
@article{arpaci2016-242938,
author = {Arpaci, Hande and Comu, Faruk Metin and Kucuk, Aysegul and Kosem, Bahadir and Kartal, Seyfi and ŞIVGIN, VOLKAN and Turgut, Huseyin Cihad and Aydın, Muhammed Enes and Koc, Derya Sebile and ARSLAN, MUSTAFA},
title = {Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats},
journal = {Drug Design Development and Therapy},
year = {2016},
volume = {10},
pages = {2477--2481},
issn = {1177-8881},
doi = {10.2147/dddt.s113806},
url = {https://akademik.atauni.edu.tr/yayinlar/242938-effects-of-lornoxicam-and-intravenous-ibuprofen-on-erythrocyte-deformability-and}
}