RETROSPECTIVE EVALUATION OF RELATIONSHIP BETWEEN POSTOPERATIVE COMPLICATIONS AND VITAMIN D LEVELS IN PATIENTS PERFORMED CORONARY ARTERY BYPASS GRAFTING OPERATION

Objectives: Although low levels of Vitamin D (VD) are considered an important risk factor in coronary artery disease (CAD)

due to its negative effects on vascular structures, the relationship between VD deficiency and postoperative complications of

coronary artery bypass grafting (CABG) operations is not clear. In present study, we aimed to investigate the relationship

between postoperative complications and VD levels in patients who underwent CABG. Methods: 150 patients who were

decided to have CABG operation and whose VD levels were measured in the preoperative period were included in the study.

The data were analyzed retrospectively, and 150 patients were divided into control group (Group A; 25-80 ng/mL) and VD

deficiency group (Group B; <25ng/mL) according to their VD levels. Preoperative, intraoperative and postoperative data were

recorded. Deaths within the first 30 days were accepted as mortality and morbidity during hospitalization were accepted as

complications. Results: Group A consisted of 75 patients (Male/Female; 53/22) with a VD level of 25-80 ng/mL and mean age

was 60.2±9.2 years, and Group B consisted of 75 patients (Male/Female; 48/27) with a VD value of <25 ng/mL and mean age

was 62.08±8.9 years. There was no difference between the groups in terms of gender (p=0.243), age (p=0.232), BMI (p=0.137),

and EuroScore (p=0.512). Mean of VD levels were 42.6±13.8 ng/mL in Group A and 10.08±5.7 ng/mL in Group B. (p<0.01)

Cardiopulmonary bypass (CPB; p=0.874) and aortic cross-clamp (ACC; p=0.495) times were longer in Group B. The number

of anatomoses was higher in Group A than Group B (3.27±0.79 and 2.80±0.88, respectively) (p=0.01) but the need for positive

inotropic support was higher in Group B patients. (p=0.03) The cumulative mortality rate was 3.3% (Group A/B:2/3).