Atatürk Üniversitesi Atatürk Üniversitesi
Ara
Yayınlara dön
Makale Tam Makale Ulusal 2022 Açık erişimli

CORRELATION OF MATERNAL BLOOD, CORD BLOOD AND PLACENTAL TISSUE MALONDIALDEHYDE LEVELS WITH FETOMATERNAL DOPPLERVALUES IN PREECLAMPTIC PREGNANT WOMEN

Esra Çınar Tanrıverdi, H. Alper Tanrıverdi, Ayşe Semra Demir Akca

atatürk üniversitesi cerrahi tıp bilimleri dergisi Cilt 1 · Sayı 3 · ss. 89–96 · 01.12.2022

Özet

Objective: In this study, it was aimed to evaluate the correlation of malondialdehyde (MDA) levels in maternal blood, fetal

blood, and placental bed with fetomaternal Doppler values in preeclamptic pregnant women. Methods: The study was carried

out with a total of 74 cases, of whom 52 were healthy and 22 were pregnant with preeclampsia. Malondialdehyde levels were

measured in maternal blood, cord blood, and placenta tissues of the pregnant women. Doppler sonographic measurements were

carried out for the uterine and umbilical arteries. Doppler values and MDA levels of preeclamptic and healthy pregnant women

were compared. Results: Malondialdehyde levels in maternal blood and placental tissue in preeclamptic pregnant women were

significantly higher than healthy pregnant women (p<0.05). Although umbilical artery and umbilical vein MDA levels were

higher in the study group than in the control group, they were not statistically significant (p>0.05). Doppler sonographic indexes

in the umbilical and uterine arteries were significantly higher in the preeclamptic group than in the control group (p<0.05).

When all patients were evaluated, there was no significant correlation between maternal and placental malondialdehyde values

and umbilical and uterine artery Doppler values. Conclusion: Malondialdehyde levels and fetomaternal Doppler values in

blood and placental tissue were significantly higher in preeclamptic pregnant women compared to the control group. However,

no significant correlation was found between MDA levels and Doppler values.

Keywords: Oxidative stress, lipid peroxidation, malondialdehyde, Doppler sonography, placental insufficiency,

preeclampsia

Atıf için künye

Çınar Tanrıverdi, E., Tanrıverdi, H. A., & Demir Akca, A. S. (2022). CORRELATION OF MATERNAL BLOOD, CORD BLOOD AND PLACENTAL TISSUE MALONDIALDEHYDE LEVELS WITH FETOMATERNAL DOPPLERVALUES IN PREECLAMPTIC PREGNANT WOMEN. atatürk üniversitesi cerrahi tıp bilimleri dergisi, 1(3), 89–96. https://dergipark.org.tr/tr/download/article-file/2825111

BibTeX 
@article{cinartanriverdi2022-238859,
  author = {Çınar Tanrıverdi, Esra and Tanrıverdi, H. Alper and Demir Akca, Ayşe Semra},
  title = {CORRELATION OF MATERNAL BLOOD, CORD BLOOD AND PLACENTAL TISSUE MALONDIALDEHYDE LEVELS WITH FETOMATERNAL DOPPLERVALUES IN PREECLAMPTIC PREGNANT WOMEN},
  journal = {atatürk üniversitesi cerrahi tıp bilimleri dergisi},
  year = {2022},
  volume = {1},
  number = {3},
  pages = {89--96},
  issn = {2822-3519},
  url = {https://akademik.atauni.edu.tr/yayinlar/238859-correlation-of-maternal-blood-cord-blood-and-placental-tissue-malondialdehyde}
}