Investigation of BRAF mutation analysis with different technical platforms in metastatic melanoma
Özet
In metastatic melanoma, the detection of somatic mutations in the BRAF gene is crucial regarding patient selection for targeted therapy. Several screening methods have been developed to identify BRAF gene mutations. In this study, our objective was to evaluate the detection of the BRAF V600 mutations using two molecular methods, real-time polymerase chain (real-time PCR) assay and pyrosequencing, and immunohistochemistry (IHC), and to compare the results of these different technical platforms.
Atıf için künye
Şener, E., YİLDİRİM, P., Tan, A., GÖKÖZ, Ö., & Tezel, G. G. (2017). Investigation of BRAF mutation analysis with different technical platforms in metastatic melanoma. PATHOLOGY RESEARCH AND PRACTICE, 213(5), 522–530. https://doi.org/10.1016/j.prp.2017.01.010
BibTeX
@article{sener2017-238570,
author = {Şener, Ebru and YİLDİRİM, Pinar and Tan, Ayca and GÖKÖZ, ÖZAY and Tezel, Gaye Guler},
title = {Investigation of BRAF mutation analysis with different technical platforms in metastatic melanoma},
journal = {PATHOLOGY RESEARCH AND PRACTICE},
year = {2017},
volume = {213},
number = {5},
pages = {522--530},
issn = {0344-0338},
doi = {10.1016/j.prp.2017.01.010},
url = {https://akademik.atauni.edu.tr/yayinlar/238570-investigation-of-braf-mutation-analysis-with-different-technical-platforms-in}
}