Comparison of multiplex real-time polymerase chain reaction with serological tests and culture for diagnosing human brucellosis

Dal, Tuba; Kara, Soner Sertan; Cikman, Aytekin; Balkan, Cigdem Eda; Acikgoz, Ziya Cibali; Zeybek, Hasan; Uslu, Hakan; Durmaz, Riza

doi:10.1016/j.jiph.2018.11.008

Makale Tam Makale Uluslararası 2019

Comparison of multiplex real-time polymerase chain reaction with serological tests and culture for diagnosing human brucellosis

Tuba Dal, Soner Sertan Kara, Aytekin Cikman, Cigdem Eda Balkan, Ziya Cibali Acikgoz, Hasan Zeybek, Hakan Uslu, Riza Durmaz

JOURNAL OF INFECTION AND PUBLIC HEALTH Cilt 12 · Sayı 3 · ss. 337–342 · 01.05.2019

DOI ile aç

Özet

Objective: Brucellosis is a zoonotic disease with various clinical presentations and early diagnosis is crucial to avoid severe complications. Due to limitations of conventional diagnostic methods, polymerase chain reaction (PCR) based approaches have gained importance in diagnosis. We aimed to evaluate diagnostic value of multiplex real time-PCR (mRT-PCR) in serum samples collected from brucellosis suspected patients by comparision sensitivity of mRT-PCR with those of conventional diagnostic methods.

Anahtar kelimeler

CULTURE Brucellosis Multiplex real-time PCR Serological diagnosis PCR ASSAY

Sürdürülebilir Kalkınma Amaçları

SKA 3: Sağlıklı Bireyler

Atıf için künye

Dal, T., Kara, S. S., Cikman, A., Balkan, C. E., Acikgoz, Z. C., Zeybek, H., Uslu, H., & Durmaz, R. (2019). Comparison of multiplex real-time polymerase chain reaction with serological tests and culture for diagnosing human brucellosis. JOURNAL OF INFECTION AND PUBLIC HEALTH, 12(3), 337–342. https://doi.org/10.1016/j.jiph.2018.11.008

BibTeX

@article{dal2019-236094,
  author = {Dal, Tuba and Kara, Soner Sertan and Cikman, Aytekin and Balkan, Cigdem Eda and Acikgoz, Ziya Cibali and Zeybek, Hasan and Uslu, Hakan and Durmaz, Riza},
  title = {Comparison of multiplex real-time polymerase chain reaction with serological tests and culture for diagnosing human brucellosis},
  journal = {JOURNAL OF INFECTION AND PUBLIC HEALTH},
  year = {2019},
  volume = {12},
  number = {3},
  pages = {337--342},
  issn = {1876-0341},
  doi = {10.1016/j.jiph.2018.11.008},
  url = {https://akademik.atauni.edu.tr/yayinlar/236094-comparison-of-multiplex-real-time-polymerase-chain-reaction-with-serological}
}