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Makale Tam Makale Uluslararası 2021

Protective effect of Coenzyme Q10 on oxidative ovarian and uterine damage induced by methotrexate in rats

T. Kiremitli, S. Kiremitli, B. Akselim, B. Yilmaz, R. Mammadov, I. H. Tor, G. N. Yazici, Mine Gülaboğlu

Human & experimental toxicology Cilt 40 · Sayı 9 · ss. 1537–1544 · 01.09.2021
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Özet

Methotrexate (MTX) has toxic effects on the uterus and ovaries via oxidative stress. Coenzyme Q10 (CoQ10) is an important component in electron transport in the mitochondria and an antioxidant in cellular metabolism through the inhibition of lipid peroxidation. The aim of this study was to investigate the preventive effects of CoQ10 on MTX-induced utero-ovarian damage and oxidative stress in rats.

Anahtar kelimeler

oxidative stress ANTIOXIDANTS LIPID-PEROXIDATION Methotrexate Coenzyme Q10

Atıf için künye

Kiremitli, T., Kiremitli, S., Akselim, B., Yilmaz, B., Mammadov, R., Tor, I. H., Yazici, G. N., & Gülaboğlu, M. (2021). Protective effect of Coenzyme Q10 on oxidative ovarian and uterine damage induced by methotrexate in rats. Human & experimental toxicology, 40(9), 1537–1544. https://doi.org/10.1177/09603271211002891

BibTeX 
@article{kiremitli2021-23418,
  author = {Kiremitli, T. and Kiremitli, S. and Akselim, B. and Yilmaz, B. and Mammadov, R. and Tor, I. H. and Yazici, G. N. and Gülaboğlu, Mine},
  title = {Protective effect of Coenzyme Q10 on oxidative ovarian and uterine damage induced by methotrexate in rats},
  journal = {Human & experimental toxicology},
  year = {2021},
  volume = {40},
  number = {9},
  pages = {1537--1544},
  issn = {0960-3271},
  doi = {10.1177/09603271211002891},
  url = {https://akademik.atauni.edu.tr/yayinlar/23418-protective-effect-of-coenzyme-q10-on-oxidative-ovarian-and-uterine-damage}
}