Mitochondrial DNA deletions in patients with esophagitis, Barrett's esophagus, esophageal adenocarcinoma and squamous cell carcinoma
Özet
Background: Esophageal cancer is the eighth most common cancer globally. Esophageal adenocarcinoma (EA) and esophageal squamous-cell carcinoma (ESCC) are the two major types of esophageal cancer with poor prognosis. The mechanisms of the progression of normal esophagus to Barrett's esophagus (BE) and EA are not fully understood. Mitochondria play a central role in generating energy, apoptosis and cell proliferation. Mutations of mitochondrial DNA (mtDNA) have been identified in many diseases including cancers. Mutations of mtDNA were investigated as a part of carcinogenesis.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
KELEŞ, M., Sahin, I., Kurt, A., Bozoglu, C., Simsek, G., Kabalar, E., & Tatar, A. (2019). Mitochondrial DNA deletions in patients with esophagitis, Barrett's esophagus, esophageal adenocarcinoma and squamous cell carcinoma. AFRICAN HEALTH SCIENCES, 19(1), 1671–1676. https://doi.org/10.4314/ahs.v19i1.43
BibTeX
@article{keles2019-233349,
author = {KELEŞ, Muzaffer and Sahin, Ibrahim and Kurt, Ali and Bozoglu, Ceyda and Simsek, Gulcin and Kabalar, Esref and Tatar, Abdulgani},
title = {Mitochondrial DNA deletions in patients with esophagitis, Barrett's esophagus, esophageal adenocarcinoma and squamous cell carcinoma},
journal = {AFRICAN HEALTH SCIENCES},
year = {2019},
volume = {19},
number = {1},
pages = {1671--1676},
issn = {1680-6905},
doi = {10.4314/ahs.v19i1.43},
url = {https://akademik.atauni.edu.tr/yayinlar/233349-mitochondrial-dna-deletions-in-patients-with-esophagitis-barretts-esophagus}
}