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Makale Tam Makale Uluslararası 2015

The critical role of spinal 5-HT7 receptors in opioid and non-opioid type stress-induced analgesia

Ozgur YESILYURT, Melik SEYREK, Serdar TASDEMIR, Serdar KAHRAMAN, Mehmet Salih DEVECI, Emre Karakus, Zekai Halıcı, Ahmet DOGRUL

EUROPEAN JOURNAL OF PHARMACOLOGY Cilt 762 · ss. 402–410 · 05.09.2015
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Özet

The opioid and non-opioid types of stress-induced analgesia have been well defined. One of the non-opioid type involve the endocannabinoid system. We previously reported that the spinal serotonin 7 receptor (5-HT7) blockers inhibit both morphine and cannabinoid-induced analgesia, thus we hypothesized that descending serotonergic pathways spinal 5-HT7 receptor loop might contribute to stress induced analgesia.

Anahtar kelimeler

PAIN Activation MODULATION MORPHINE MECHANISM Serotonin 5-HT7 receptors INVOLVEMENT PEPTIDES STRESS-INDUCED ANALGESIA DESCENDING SEROTONERGIC PATHWAYS SWIM STRESS ANTINOCICEPTION

Atıf için künye

YESILYURT, O., SEYREK, M., TASDEMIR, S., KAHRAMAN, S., DEVECI, M. S., Karakus, E., Halıcı, Z., & DOGRUL, A. (2015). The critical role of spinal 5-HT7 receptors in opioid and non-opioid type stress-induced analgesia. EUROPEAN JOURNAL OF PHARMACOLOGY, 762, 402–410. https://doi.org/10.1016/j.ejphar.2015.04.020

BibTeX 
@article{yesilyurt2015-232952,
  author = {YESILYURT, Ozgur and SEYREK, Melik and TASDEMIR, Serdar and KAHRAMAN, Serdar and DEVECI, Mehmet Salih and Karakus, Emre and Halıcı, Zekai and DOGRUL, Ahmet},
  title = {The critical role of spinal 5-HT7 receptors in opioid and non-opioid type stress-induced analgesia},
  journal = {EUROPEAN JOURNAL OF PHARMACOLOGY},
  year = {2015},
  volume = {762},
  pages = {402--410},
  issn = {0014-2999},
  doi = {10.1016/j.ejphar.2015.04.020},
  url = {https://akademik.atauni.edu.tr/yayinlar/232952-the-critical-role-of-spinal-5-ht7-receptors-in-opioid-and-non-opioid-type-stress}
}