A Preliminary Study of Serum Apelin Levels in Patients with Head and Neck Cancer
Özet
Objective: Treatment planning is primarily based on the tumor node metastasis (TNM) staging system for head and neck cancer (HNC). However, TNM does not give sufficient information about biological aggressiveness, treatment response, and prognosis. New molecular markers are needed for individualized cancer treatment. Apelin is a bioactive peptide and an endogenous ligand for the G protein-coupled receptor (APJ). Its expression is induced under hypoxic conditions. Apelin and its receptor APJ are important factors in physiological angiogenesis and may be novel targets for anti-angiogenic tumor therapies. This preliminary study aimed to investigate whether there was a difference in serum apelin levels between patients with HNC and control group and also to compare the serum apelin levels before and after radiotherapy.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Aktan, M., & Kızıltunç Özmen, H. (2019). A Preliminary Study of Serum Apelin Levels in Patients with Head and Neck Cancer. EURASIAN JOURNAL OF MEDICINE, 51(1), 57–59. https://doi.org/10.5152/eurasianjmed.2018.18411
BibTeX
@article{aktan2019-229530,
author = {Aktan, Meryem and Kızıltunç Özmen, Hilal},
title = {A Preliminary Study of Serum Apelin Levels in Patients with Head and Neck Cancer},
journal = {EURASIAN JOURNAL OF MEDICINE},
year = {2019},
volume = {51},
number = {1},
pages = {57--59},
issn = {1308-8734},
doi = {10.5152/eurasianjmed.2018.18411},
url = {https://akademik.atauni.edu.tr/yayinlar/229530-a-preliminary-study-of-serum-apelin-levels-in-patients-with-head-and-neck-cancer}
}