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Makale Tam Makale Uluslararası 2021 Açık erişimli

The role of melatonin in preventing radiation-induced intestinal injury

Orhan Sezen, Burak Erdemci, Muhammet Çalık, Mehmet Koc

JOURNAL OF BUON Cilt 26 · Sayı 2 · ss. 626–633 · 01.03.2021

Özet

Purpose: Despite the therapeutic effects of radiotherapy on tumor cells, it has potential severe adverse effects on the sur- rounding normal tissues. Acute or chronic intestinal adverse effects that are likely to occur in patients undergoing radio- therapy for pelvic and abdominal cancers lead to increased morbidity, significant impairment of the quality of life, and economic losses. Various biological, chemical and pharma- cological agents are being tested to protect from and to treat radiation enteritis. This experimental study aimed to inves- tigate the protective effects of melatonin against radiation induced intestinal injury when administered before radiation exposure in rats.

Anahtar kelimeler

radiotherapy melatonin Radioprotective intestinal injury radiation enteritis

Sürdürülebilir Kalkınma Amaçları

  • SKA 3: Sağlıklı Bireyler

Atıf için künye

Sezen, O., Erdemci, B., Çalık, M., & Koc, M. (2021). The role of melatonin in preventing radiation-induced intestinal injury. JOURNAL OF BUON, 26(2), 626–633.

BibTeX
@article{sezen2021-229482,
  author = {Sezen, Orhan and Erdemci, Burak and Çalık, Muhammet and Koc, Mehmet},
  title = {The role of melatonin in preventing radiation-induced intestinal injury},
  journal = {JOURNAL OF BUON},
  year = {2021},
  volume = {26},
  number = {2},
  pages = {626--633},
  issn = {1107-0625},
  url = {https://akademik.atauni.edu.tr/yayinlar/229482-the-role-of-melatonin-in-preventing-radiation-induced-intestinal-injury}
}