The Effect of Sodium Pertechnetate Human Carbonic Anhydrase I and II
Özet
The inhibitory effects of (NaTcO4)-Tc-99m (Sodium pertechnetate) on human erythrocyte carbonic anhydrase I and II activity were investigated. For this purpose, hCA I was initially purified 114,29-fold at a yield of 69,19 % and hCA II was initially purified 710,82-fold at a yield of 71,72 % using sepharose 4B-tyrosine-sulfanilamide affinity gel chromatography. The in vitro effect of this compound on hCA I and II isoenzyme were studied. It was detected in in vitro studies that the hCA I and II enzymes are inhibited due to (NaTcO4)-Tc-99m.
Atıf için künye
Şahin, A., & ŞENTÜRK, M. (2017). The Effect of Sodium Pertechnetate Human Carbonic Anhydrase I and II. International Conference on Advances in Natural and Applied Sciences (ICANAS), Antalya. https://doi.org/10.1063/1.4981758
BibTeX
@inproceedings{sahin2017-229246,
author = {Şahin, Ali and ŞENTÜRK, MURAT},
title = {The Effect of Sodium Pertechnetate Human Carbonic Anhydrase I and II},
booktitle = {International Conference on Advances in Natural and Applied Sciences (ICANAS)},
address = {Antalya},
year = {2017},
doi = {10.1063/1.4981758},
url = {https://akademik.atauni.edu.tr/yayinlar/229246-the-effect-of-sodium-pertechnetate-human-carbonic-anhydrase-i-and-ii}
}