Pathologic and Clinical Characteristics of Elderly Patients With Breast Cancer: A Retrospective Analysis of a Multicenter Study (Anatolian Society of Medical Oncology)
Özet
There is very little information about breast cancer characteristics, treatment choices, and survival among elderly patients. The purpose of this multicenter retrospective study was to examine the clinical, pathologic, and biologic characteristics of 620 breast cancer patients age 70 years or older. Between June 1991 and May 2012, 620 patients with breast cancer, recruited from 16 institutions, were enrolled in the retrospective study. Patients had smaller tumors at diagnosis; only 15% of patients had tumors larger than 5 cm. The number of patients who had no axillary lymph node involvement was 203 (32.7%). Ninety-three patients (15.0%) had metastatic disease at diagnosis. Patients were characterized by a higher fraction of pure lobular carcinomas (75.3%). The tumors of the elderly patients were also more frequently estrogen receptor (ER) positive (75.2%) and progesterone receptor (PR) positive (67.3%). The local and systemic therapies for breast cancer differed according to age. An association between age and overall survival has not been demonstrated in elderly patients with breast cancer. In conclusion, the biologic behavior of older patients with breast cancer differs from younger patients, and older patients receive different treatments.
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Inal, A., Akman, T., Yaman, S., Ozturk, S. C., Geredeli, C., Bilici, M., İNANÇ, M., Harputoglu, H., Demirci, U., Balakan, O., Cinkir, H. Y., Alici, S., Colak, D., Sonmez, O. U., Goksel, G., DOĞU, G. G., ENGİN, H., Unal, O. U., Tamozlu, T., … Isikdogan, A. (2014). Pathologic and Clinical Characteristics of Elderly Patients With Breast Cancer: A Retrospective Analysis of a Multicenter Study (Anatolian Society of Medical Oncology). INTERNATIONAL SURGERY, 99(1), 2–7. https://doi.org/10.9738/intsurg-d-13-00010
BibTeX
@article{inal2014-228436,
author = {Inal, Ali and Akman, Tulay and Yaman, Sebnem and Ozturk, Selcuk Cemil and Geredeli, Caglayan and Bilici, Mehmet and İNANÇ, MEVLÜDE and Harputoglu, Hakan and Demirci, Umut and Balakan, Ozan and Cinkir, Havva Yesil and Alici, Suleyman and Colak, Dilsen and Sonmez, Ozlem Uysal and Goksel, Gamze and DOĞU, GAMZE GÖKÖZ and ENGİN, HÜSEYİN and Unal, Olcun Umit and Tamozlu, Tulay and Buyukberber, Suleyman and Boruban, Cem Melih and Isikdogan, Abdurrahman},
title = {Pathologic and Clinical Characteristics of Elderly Patients With Breast Cancer: A Retrospective Analysis of a Multicenter Study (Anatolian Society of Medical Oncology)},
journal = {INTERNATIONAL SURGERY},
year = {2014},
volume = {99},
number = {1},
pages = {2--7},
issn = {0020-8868},
doi = {10.9738/intsurg-d-13-00010},
url = {https://akademik.atauni.edu.tr/yayinlar/228436-pathologic-and-clinical-characteristics-of-elderly-patients-with-breast-cancer-a}
}