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Makale Tam Makale Uluslararası 2025

Three-Decade Analysis of Inflammatory Bowel Disease in Türkiye: A Multicenter Study (1993-2024)

Muhammed Bahaddin Durak, Yasir Furkan Cagin, Ayhan Balkan, Yusuf Coskun, Tarkan Karakan, Yavuz Cagir, Yavuz Beyazit, Ali Atay, Ali Can Erdem, Guray Can, Engin Altinkaya, Hakan Dursun, Orhan Coskun, Mehmet Rasit Ayte, Mevlut Hamamci, Ilyas Tenlik, Cem Simsek, Abdurrahman Sahin, Huseyin Koseoglu, Mustafa Akar, Kenan Kosar, Bülent Albayrak, Eylem Karatay, Murat Kekilli, Mehmet Asil, Hilmi Ataseven, Mehmet Cindoruk, Ilhami Yuksel

TURKISH JOURNAL OF GASTROENTEROLOGY Cilt 36 · Sayı 12 · 01.12.2025
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Özet

Background/Aims: Inflammatory bowel diseases (IBDs) are increasingly prevalent and challenging globally. Data regarding IBD fre quency and severity between Europe and Asia are needed. The aim was to investigate the trend of IBD in T & uuml;rkiye during the last 3 decades. Materials and Methods: The study was conducted retrospectively at 14 centers in T & uuml;rkiye between June 1993 and March 2024. Results: Over 30 years, 4308 patients, of whom 2507 (58.2%) had ulcerative colitis (UC) and 1717 (39.9%) had Crohn's Disease (CD), were included in the study. The overall median age at the onset of IBD was 34.43 (25.28-45.64) years; the age at onset of IBD was younger in CD compared to UC (32.72 vs. 35.52 years respectively, P < .001). The peak age onset range was 28-32 years in CD, whereas 23-27 years in UC. Overall, 2526 (58.6%) patients were male. The most common location was left-sided colitis in UC patients (45.1%), followed by extensive colitis (31.2%), and proctitis (23.7%), while ileal involvement in CD patients (45.2%), afterward ileocolonic (409%), and colonic (13.5%). Both illnesses are becoming increasingly prevalent. The UC/CD ratio tends to decrease over time. During the study period, 1577 (36.6%) patients received biologic treatment. During the study period, 418 (24.3%) underwent resective surgery for CD and 88 (3.5%) total colectomy for UC; the major abdominal surgery has declined over time. Conclusion: The frequency and characteristic features of IBD in T & uuml;rkiye appear to be between Europe and Asia. Over time, while the usage of biologic therapy and the rate of CD have increased, the frequency of surgery has decreased.

Anahtar kelimeler

Inflammatory bowel disease ulcerative colitis Crohn’s disease

Atıf için künye

Durak, M. B., Cagin, Y. F., Balkan, A., Coskun, Y., Karakan, T., Cagir, Y., Beyazit, Y., Atay, A., Erdem, A. C., Can, G., Altinkaya, E., Dursun, H., Coskun, O., Ayte, M. R., Hamamci, M., Tenlik, I., Simsek, C., Sahin, A., Koseoglu, H., … Yuksel, I. (2025). Three-Decade Analysis of Inflammatory Bowel Disease in Türkiye: A Multicenter Study (1993-2024). TURKISH JOURNAL OF GASTROENTEROLOGY, 36(12). https://doi.org/10.5152/tjg.2025.25063

BibTeX 
@article{durak2025-228230,
  author = {Durak, Muhammed Bahaddin and Cagin, Yasir Furkan and Balkan, Ayhan and Coskun, Yusuf and Karakan, Tarkan and Cagir, Yavuz and Beyazit, Yavuz and Atay, Ali and Erdem, Ali Can and Can, Guray and Altinkaya, Engin and Dursun, Hakan and Coskun, Orhan and Ayte, Mehmet Rasit and Hamamci, Mevlut and Tenlik, Ilyas and Simsek, Cem and Sahin, Abdurrahman and Koseoglu, Huseyin and Akar, Mustafa and Kosar, Kenan and Albayrak, Bülent and Karatay, Eylem and Kekilli, Murat and Asil, Mehmet and Ataseven, Hilmi and Cindoruk, Mehmet and Yuksel, Ilhami},
  title = {Three-Decade Analysis of Inflammatory Bowel Disease in Türkiye: A Multicenter Study (1993-2024)},
  journal = {TURKISH JOURNAL OF GASTROENTEROLOGY},
  year = {2025},
  volume = {36},
  number = {12},
  issn = {2148-5607},
  doi = {10.5152/tjg.2025.25063},
  url = {https://akademik.atauni.edu.tr/yayinlar/228230-three-decade-analysis-of-inflammatory-bowel-disease-in-turkiye-a-multicenter}
}