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Makale Tam Makale Uluslararası 2012

Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver

İSMAİL DEMİRYILMAZ, Ebru Şener, NİHAL ÇETİN, DURDU ALTUNER, BAHADIR SÜLEYMAN, Fatih Albayrak, Fatih Akçay, HALİS SÜLEYMAN

Medical science monitor : international medical journal of experimental and clinical research Cilt 18 · Sayı 12 · 01.12.2012
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Özet

Background: Oxidative liver injury occurring with methotrexate restricts its use in the desired dose. Therefore, whether or not thiamine and thiamine pyrophosphate, whose antioxidant activity is known, have protective effects on oxidative liver injury generated with methotrexate was comparatively researched in rats using biochemical and histopathological approaches.

Anahtar kelimeler

Methotrexate Rat hepatotoxicity thiamine thiamine pyrophosphate

Atıf için künye

DEMİRYILMAZ, İ., Şener, E., ÇETİN, N., ALTUNER, D., SÜLEYMAN, B., Albayrak, F., Akçay, F., & SÜLEYMAN, H. (2012). Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver. Medical science monitor : international medical journal of experimental and clinical research, 18(12). https://doi.org/10.12659/msm.883591

BibTeX
@article{demiryilmaz2012-228085,
  author = {DEMİRYILMAZ, İSMAİL and Şener, Ebru and ÇETİN, NİHAL and ALTUNER, DURDU and SÜLEYMAN, BAHADIR and Albayrak, Fatih and Akçay, Fatih and SÜLEYMAN, HALİS},
  title = {Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver},
  journal = {Medical science monitor : international medical journal of experimental and clinical research},
  year = {2012},
  volume = {18},
  number = {12},
  issn = {1234-1010},
  doi = {10.12659/msm.883591},
  url = {https://akademik.atauni.edu.tr/yayinlar/228085-biochemically-and-histopathologically-comparative-review-of-thiamines-and}
}