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Makale Tam Makale Uluslararası 2008

Evaluation of nitric oxide synthase activity, nitric oxide, and homocysteine levels in patients with active Behcet's disease

Seyithan Taysi, Refik Ali SARI, Hakan Dursun, Adnan YILMAZ, Mustafa KELES, Kerim CAYİR, Mehmet AKYÜZ, Abdullah Uyanık, Adem GÜVENÇ

CLINICAL RHEUMATOLOGY Cilt 27 · Sayı 12 · ss. 1529–1534 · 01.12.2008
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Özet

Behcet's disease (BD) is a chronic, progressive disorder that affects many systems of the body including the eye. The aim of this study was to examine the effects of nitric oxide synthase activity (NOS), nitric oxide and homocysteine (Hcy) levels in patients with active BD. Included in this study were 18 male BD patients and 16 male healthy volunteers as controls. Erythrocyte NOS activity, F, erythrocyte sedimentation rate, serum C-reactive protein, and plasma Hcy values in the patients with BD were significantly higher than those of the control group. Our results show that these parameters play a major role in the inflammatory reactions observed in BD.

Anahtar kelimeler

oxidative stress NITRIC-OXIDE Rheumatoid arthritis Free radicals LIPID-PEROXIDATION glutathione peroxidase superoxide dismutase RISK-FACTOR NITRIC-OXIDE SYNTHASE homocysteine guinea pigs SERUM OXIDANT/ANTIOXIDANT STATUS EXPERIMENTAL OTITIS-MEDIA II DIABETES-MELLITUS

Atıf için künye

Taysi, S., SARI, R. A., Dursun, H., YILMAZ, A., KELES, M., CAYİR, K., AKYÜZ, M., Uyanık, A., & GÜVENÇ, A. (2008). Evaluation of nitric oxide synthase activity, nitric oxide, and homocysteine levels in patients with active Behcet's disease. CLINICAL RHEUMATOLOGY, 27(12), 1529–1534. https://doi.org/10.1007/s10067-008-0963-4

BibTeX 
@article{taysi2008-227949,
  author = {Taysi, Seyithan and SARI, Refik Ali and Dursun, Hakan and YILMAZ, Adnan and KELES, Mustafa and CAYİR, Kerim and AKYÜZ, Mehmet and Uyanık, Abdullah and GÜVENÇ, Adem},
  title = {Evaluation of nitric oxide synthase activity, nitric oxide, and homocysteine levels in patients with active Behcet's disease},
  journal = {CLINICAL RHEUMATOLOGY},
  year = {2008},
  volume = {27},
  number = {12},
  pages = {1529--1534},
  issn = {0770-3198},
  doi = {10.1007/s10067-008-0963-4},
  url = {https://akademik.atauni.edu.tr/yayinlar/227949-evaluation-of-nitric-oxide-synthase-activity-nitric-oxide-and-homocysteine}
}