Identifying future risk factors of uncontrolled asthma control: the TAAR study perspective
Özet
Objective: Risk factors associated with asthma symptom control is crucial for disease management. This study aimed to determine the risk factors of patients with uncontrolled asthma and to examine the relationship with their geographical patterns. Methods: This cross-sectional study was conducted at 36 centers across Turkey. Future risk factors (FRFs) such as exposure to triggers/allergens and inadequate or poor inhalation technique, etc., were identified based on the Global Initiative for Asthma (GINA) guidelines. The associations between FRFs and demographic and clinical characteristics, geographical regions, and levels of asthma control were analyzed. Results: The study included 2,053 adult asthma patients. At least one FRF was identified in 1576(76.8%) patients. The most common FRFs were exposure to allergens/triggers (n: 664; 32.3%), impaired asthma symptom control (n: 540; 26.3%), and eosinophilia (n: 526; 25.6%). Regarding regional differences, the most prevalent FRFs in the Marmara region were exposure to allergens/triggers and frequent use of short-acting beta-2 agonists (>3 boxes/year). In contrast, eosinophilia was more common in the Southeastern region, while inadequate or poor inhalation technique, noncompliance with treatment, and psychosocial or socioeconomic problems were more frequently observed in the Eastern Anatolia region. Asthma control was achieved in 79.5% of patients without any FRFs; however, this rate decreased significantly to 25% among patients with more than four FRFs. Conclusions: This study demonstrates that FRFs in asthma vary according to demographic and disease characteristics, as well as geographical distribution. An increased number of FRFs was associated with asthma control. However, an individualized approach remains essential for achieving optimal asthma management.
Anahtar kelimeler
Atıf için künye
BOZKURT, N., Abadoglu, O., Onaran, A. B. O., GÖKMEN, D., Buhari, G. K., AYDIN, Ö., ŞEKER, Ü., Polatli, M., Cengiz, A., Celebi Sozener, Z., Gemicioglu, B., Bulut, I., Beyaz, S., Orcen, C., Ozdemir, S. K., Keren, M., Damadoglu, E., Yakut, T., Kalpaklioglu, A. F., … Celik, G. E. (2026). Identifying future risk factors of uncontrolled asthma control: the TAAR study perspective. JOURNAL OF ASTHMA, 63(3), 339–349. https://doi.org/10.1080/02770903.2025.2592244
BibTeX
@article{bozkurt2026-227113,
author = {BOZKURT, NURGÜL and Abadoglu, Oznur and Onaran, Ayse Bilge Ozturk and GÖKMEN, DERYA and Buhari, Gozde Koycu and AYDIN, ÖMÜR and ŞEKER, ÜMMÜHAN and Polatli, Mehmet and Cengiz, Ali and Celebi Sozener, Zeynep and Gemicioglu, Bilun and Bulut, Ismet and Beyaz, Sengul and Orcen, Cihan and Ozdemir, Secil Kepil and Keren, Metin and Damadoglu, Ebru and Yakut, Tugce and Kalpaklioglu, Ayse Fusun and Baccioglu, Ayse and Yalim, Sumeyra Alan and Yilmaz, Insu and Koca Kalkan, Ilkay and Uysal, Mehmet Atilla and Ozgun Niksarlioglu, Elif Yelda and Kalyoncu, Ali Fuat and Karakaya, Gul and Erbay, Muge and Nayci, Sibel and Tepetam, Fatma Merve and Gelincik, Asli Akkor and Dirol, Hulya and Goksel, Ozlem and Karaoglanoglu, Selen and Oner Erkekol, Ferda and Isik, Sacide Rana and Yildiz, Fusun and Yavuz, Yasemin and Karadogan, Dilek and Oguzulgen, Ipek Kivilcim and Basyigit, Ilknur and Baris, Serap Argun and Yılmazel Uçar, Elif and Erdogan, Tuba and Ediger, Dane and Gunaydin, Fatma Esra and Turk, Murat and Pur, Leyla and Katran, Zeynep Yegin and Sekibag, Yonca and Aykac, Enes Furkan and Mungan, Dilsad and Gul, Ozcan and Akkurt, Bulent and Ozden, Seyma and Demir, Semra and Unal, Derya and Aslan, Ayse Feyza and Can, Ali and Gumusburun, Reyhan and Bogatekin, Gulhan and Akten, Hatice Serpil and Inan, Sinem and Erdinc, Munevver and Ogus, Aliye Candan and Kavas, Murat and Polat Yulug, Demet and Cakmak, Mehmet Erdem and Kaya, Saltuk Bugra and Alpagat, Gulistan and Ozgur, Eylem Sercan and Uzun, Oguz and Tas Gulen, Sule and Pekbak, Gulseren and Kizilirmak, Deniz and Havlucu, Yavuz and Donmez, Halil and Arslan, Bahar and Cetin, Gulden Pacaci and Soyyigit, Sadan and Kara, Bilge Yilmaz and Pasaoglu Karakis, Gulden and Dursun, Adile Berna and Kendirlinan, Resat and Sevinc, Can and Omeroglu Simsek, Gokcen and Cerci, Pamir and Yucel, Taskin and Yorulmaz, Irfan and Tezcaner, Zahide Ciler and Cadalli Tatar, Emel and Suslu, Ahmet Emre and Ozer, Serdar and Dursun, Engin and Yorgancioglu, Arzu and Celik, Gulfem Elif},
title = {Identifying future risk factors of uncontrolled asthma control: the TAAR study perspective},
journal = {JOURNAL OF ASTHMA},
year = {2026},
volume = {63},
number = {3},
pages = {339--349},
issn = {0277-0903},
doi = {10.1080/02770903.2025.2592244},
url = {https://akademik.atauni.edu.tr/yayinlar/227113-identifying-future-risk-factors-of-uncontrolled-asthma-control-the-taar-study}
}