The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study
Özet
Aim Nail involvement is common in psoriatic arthritis. This study assesses clinical characteristics, nail psoriasis prevalence, and impact of nail psoriasis on disease activity in patients with psoriatic arthritis (PsA). Method This cross-sectional multicenter study was conducted by the Turkish League Against Rheumatism using PsA patients recruited from 25 centers. Demographic and clinical characteristics of PsA patients, such as disease activity measures, quality of life, and nail involvement findings were assessed during routine follow-up examinations. Patients were divided into two groups according to the presence or absence of nail psoriasis and compared using the chi(2) test or Fisher exact test for categorical variables and the t-test or Mann-Whitney U test for continuous variables. Results In 1122 individuals with PsA, 645 (57.5%) displayed nail psoriasis. The most frequent features of fingernails were ridges (38%), followed by pitting (21%) and onycholysis (19%). More females were present in both groups (with and without nail psoriasis; 64% vs 67%, P < 0.282). Patients with nail psoriasis were older, indicated more pain and fatigue, experienced greater swelling, tender joint counts, and skin disease severity, and had a higher disease activity score compared with those without nail psoriasis (all P < 0.05). Conclusion We demonstrate an increased prevalence of nail psoriasis observed in patients with psoriatic arthritis. Patients with nail involvement experience increased disease activity, lower quality of life, and diminished mental and physical status compared with those without nail involvement.
Anahtar kelimeler
Atıf için künye
CENGİZ, G., Nas, K., KESKİN, Y., Kilic, E., Sargin, B., Kasman, S. A., ALKAN, H., ŞAHİN, N., Balta, N. C., Gezer, I. A., Keskin, D., Mulkoglu, C., REŞORLU, H., ATAMAN, Ş., Bal, A., Baykul, M., DURUÖZ, M. T., KÜÇÜKAKKAŞ, O., YURDAKUL, O. V., … Tuncer, T. (2023). The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study. INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 26(1), 43–50. https://doi.org/10.1111/1756-185x.14442
BibTeX
@article{cengiz2023-226299,
author = {CENGİZ, GİZEM and Nas, Kemal and KESKİN, Yaşar and Kilic, Erkan and Sargin, Betul and Kasman, Sevtap Acer and ALKAN, HAKAN and ŞAHİN, NİLAY and Balta, Nihan Cuzdan and Gezer, Ilknur Albayrak and Keskin, Dilek and Mulkoglu, Cevriye and REŞORLU, HATİCE and ATAMAN, ŞEBNEM and Bal, Ajda and Baykul, Merve and DURUÖZ, MEHMET TUNCAY and KÜÇÜKAKKAŞ, OKAN and YURDAKUL, OZAN VOLKAN and Alkan Melikoğlu, Meltem and AYHAN, FİKRİYE FİGEN and BODUR, HATİCE and ÇALIŞ, MUSTAFA and ÇAPKIN, ERHAN and Devrimsel, Gul and Gok, Kevser and HİZMETLİ, SAMİ and KAMANLI, AYHAN and Ecesoy, Hilal and Kutluk, Oznur and Sen, Nesrin and ŞENDUR, ÖMER FARUK and TEKEOĞLU, İBRAHİM and Toprak, Murat and Tolu, Sena and Tuncer, Tiraje},
title = {The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study},
journal = {INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES},
year = {2023},
volume = {26},
number = {1},
pages = {43--50},
issn = {1756-1841},
doi = {10.1111/1756-185x.14442},
url = {https://akademik.atauni.edu.tr/yayinlar/226299-the-impact-of-nail-psoriasis-on-disease-activity-quality-of-life-and-clinical}
}