Beyond expectations: disease duration and psychological burden in psoriatic arthritis
Özet
This study aims to investigate the relationship between disease duration and psychological burden in PsA and to identify the risk factors associated with psychological distress. Patients with PsA who met CASPAR classification criteria enrolled by Turkish League Against Rheumatism (TLAR)-Network. Patients were categorized into three groups based on disease duration: early stage (< 5 years), middle stage (≥ 5, < 10 years), and late stage (≥ 10 years). All patients underwent clinical and laboratory assessment using standardized protocol and case report forms. The associations between psychological variables and clinical parameters were assessed by a multivariate analysis. Of the 1113 patients with PsA (63.9% female), 564 (%50.7) had high risk for depression and 263 (%23.6) for anxiety. The risk of psychological burden was similar across all PsA groups, and patients with a higher risk of depression and anxiety also experienced greater disease activity, poorer quality of life, and physical disability. Multivariate logistic regression revealed that female gender (OR = 1.52), PsAQoL (OR = 1.13), HAQ (OR = 1.99), FiRST score (OR = 1.14), unemployment/retired (OR = 1.48) and PASI head score (OR = 1.41) were factors that influenced the risk of depression, whereas the current or past enthesitis (OR = 1.45), PsAQoL (OR = 1.19), and FiRST score (OR = 1.26) were factors that influenced the risk of anxiety. PsA patients can experience a comparable level of psychological burden throughout the course of their disease. Several socio-demographic and disease-related factors may contribute to mental disorders in PsA. In the present era of personalized treatment for PsA, evaluating psychiatric distress can guide tailored interventions that improve overall well-being and reduce disease burden.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
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SKA 8: İnsana Yakışır İş ve Ekonomik Büyüme
Atıf için künye
KILIÇ, G., Kılıç, E., Tekeoğlu, İ., Sargın, B., CENGİZ, G., Balta, N. C., Alkan, H., Kasman, S. A., Şahin, N., Orhan, K., Gezer, İ. A., Keskin, D., Mülkoğlu, C., Reşorlu, H., Ataman, Ş., Bal, A., Duruöz, M. T., Küçükakkaş, O., Şen, N., … Nas, K. (2023). Beyond expectations: disease duration and psychological burden in psoriatic arthritis. RHEUMATOLOGY INTERNATIONAL, 43(9), 1695–1704. https://doi.org/10.1007/s00296-023-05379-2
BibTeX
@article{kilic2023-226201,
author = {KILIÇ, GAMZE and Kılıç, Erkan and Tekeoğlu, İbrahim and Sargın, Betül and CENGİZ, GİZEM and Balta, Nihan Cüzdan and Alkan, Hakan and Kasman, Sevtap Acer and Şahin, Nilay and Orhan, Kevser and Gezer, İlknur Albayrak and Keskin, Dilek and Mülkoğlu, Cevriye and Reşorlu, Hatice and Ataman, Şebnem and Bal, Ajda and Duruöz, Mehmet Tuncay and Küçükakkaş, Okan and Şen, Nesrin and Toprak, Murat and Yurdakul, Ozan Volkan and Alkan Melikoğlu, Meltem and Ayhan, Fikriye Figen and Baykul, Merve and Bodur, Hatice and Çalış, Mustafa and Çapkın, Erhan and Devrimsel, Gül and Hizmetli, Sami and Kamanlı, Ayhan and Keskin, Yaşar and Ecesoy, Hilal and Kutluk, Öznur and Şendur, Ömer Faruk and Tolu, Sena and Tuncer, Tiraje and Nas, Kemal},
title = {Beyond expectations: disease duration and psychological burden in psoriatic arthritis},
journal = {RHEUMATOLOGY INTERNATIONAL},
year = {2023},
volume = {43},
number = {9},
pages = {1695--1704},
issn = {0172-8172},
doi = {10.1007/s00296-023-05379-2},
url = {https://akademik.atauni.edu.tr/yayinlar/226201-beyond-expectations-disease-duration-and-psychological-burden-in-psoriatic}
}