Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi-center study
Özet
This article aims to evaluate the possible effect of obesity on quality of life, psychological status, and other clinical variables in Psoriatic arthritis (PsA). PsA patients have been recruited by the Turkish League Against Rheumatism-Network from various centers in Turkey in this cross-sectional study. Patients with a body mass index (BMI) >= of 30 kg/m(2) were considered obese. Differences among patients with regard to obesity status were assessed with health-related quality of life measures (PsA Quality of Life Questionnaire [PsAQoL]), psychological status (Hospital Anxiety and Depression Scale [HADS]), and disease activity parameters (the Disease Activity index for PSoriatic Arthritis [DAPSA], Disease Activity Score 28-C-reactive protein [DAS28-CRP], Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Psoriasis Area and Severity Index [PASI]), physical functions (Ankylosing Spondylitis Functional Index [BASFI], Health Assessment Questionnaire [HAQ], and Health Assessment Questionnaire for the spondyloarthropathies [HAQ-S]). Pain was assessed using visual analog scale of pain (VAS-P), and fatigue was evaluated using visual analog scale of fatigue (VAS-F) and Functional Assessment of Chronic Illness Therapy (FACIT). A total of 1033 patients with PsA, 650 (62.9%) non-obese and 383 (37.1%) obese were included in the study. The PsAQoL, HADS-Anxiety, HADS-Depression, DAPSA, DAS28-CRP, BASDAI, BASFI, HAQ and HAQ-S scores of the obese group were higher than the non-obese group (p < 0.05). VAS-P and PASI scores were similar between group of patients with and without obesity. Obese patients had higher median scores of VAS-F and FACIT than non-obese patients (p < 0.05). Linear regression analysis showed that BMI affects the quality of life, depression, and disease activity. Consequently, obesity has significant associations with higher disease activity, lower QoL, risk of anxiety, depression, and fatigue. Therefore, obesity should also be taken into account in the management of PsA patients.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Gok, K., Nas, K., TEKEOĞLU, İ., Sunar, I., KESKİN, Y., Kilic, E., Sargin, B., Kasman, S. A., ALKAN, H., ŞAHİN, N., CENGİZ, G., Cuzdan, N., Gezer, I. A., Keskin, D., Mulkoglu, C., REŞORLU, H., Bal, A., DURUÖZ, M. T., KÜÇÜKAKKAŞ, O., … TUNCER, T. (2022). Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi-center study. RHEUMATOLOGY INTERNATIONAL, 42(4), 659–668. https://doi.org/10.1007/s00296-021-04971-8
BibTeX
@article{gok2022-226193,
author = {Gok, Kevser and Nas, Kemal and TEKEOĞLU, İBRAHİM and Sunar, Ismihan and KESKİN, Yaşar and Kilic, Erkan and Sargin, Betul and Kasman, Sevtap Acer and ALKAN, HAKAN and ŞAHİN, NİLAY and CENGİZ, GİZEM and Cuzdan, Nihan and Gezer, Ilknur Albayrak and Keskin, Dilek and Mulkoglu, Cevriye and REŞORLU, HATİCE and Bal, Ajda and DURUÖZ, MEHMET TUNCAY and KÜÇÜKAKKAŞ, Okan and YURDAKUL, Ozan Volkan and Alkan Melikoğlu, Meltem and Aydin, Yildiray and AYHAN, FİKRİYE FİGEN and BODUR, HATİCE and ÇALIŞ, MUSTAFA and ÇAPKIN, ERHAN and DEVRİMSEL, GÜL and Ecesoy, Hilal and HİZMETLİ, SAMİ and KAMANLI, AYHAN and Kutluk, Oznur and Sen, Nesrin and Sendur, Omer Faruk and Tolu, Sena and Toprak, Murat and TUNCER, TİRAJE},
title = {Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi-center study},
journal = {RHEUMATOLOGY INTERNATIONAL},
year = {2022},
volume = {42},
number = {4},
pages = {659--668},
issn = {0172-8172},
doi = {10.1007/s00296-021-04971-8},
url = {https://akademik.atauni.edu.tr/yayinlar/226193-impact-of-obesity-on-quality-of-life-psychological-status-and-disease-activity}
}