Clinicopathological profile of peritoneal tuberculosis and a new scoring model for predicting mortality: an international ID-IRI study
Özet
Existing literature about peritoneal tuberculosis (TBP) is relatively insufficient. The majority of reports are from a single center and do not assess predictive factors for mortality. In this international study, we investigated the clinicopathological characteristics of a large series of patients with TBP and determined the key features associated with mortality. TBP patients detected between 2010 and 2022 in 38 medical centers in 13 countries were included in this retrospective cohort. Participating physicians filled out an online questionnaire to report study data. In this study, 208 patients with TBP were included. Mean age of TBP cases was 41.4 ± 17.5 years. One hundred six patients (50.9%) were females. Nineteen patients (9.1%) had HIV infection, 45 (21.6%) had diabetes mellitus, 30 (14.4%) had chronic renal failure, 12 (5.7%) had cirrhosis, 7 (3.3%) had malignancy, and 21 (10.1%) had a history of immunosuppressive medication use. A total of 34 (16.3%) patients died and death was attributable to TBP in all cases. A pioneer mortality predicting model was established and HIV positivity, cirrhosis, abdominal pain, weakness, nausea and vomiting, ascites, isolation of Mycobacterium tuberculosis in peritoneal biopsy samples, TB relapse, advanced age, high serum creatinine and ALT levels, and decreased duration of isoniazid use were significantly related with mortality (p < 0.05). This is the first international study on TBP and is the largest case series to date. We suggest that using the mortality predicting model will allow early identification of high-risk patients likely to die of TBP.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
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SKA 16: Barış, Adalet ve Güçlü Kurumlar
Atıf için künye
Tanoglu, A., Erdem, H., Friedland, J. S., Ankaralı, H., Garcia-Goez, J. F., Albayrak, A., El-Kholy, A., Ceviker, S. A., Amer, F., Erol, S., Darazam, I. A., Rabiei, M. M., Sarwar, M. Z., Zeb, M., Nawaz, H., Ceylan, M. R., Cernat, R., Tasbakan, M., Ayoade, F., … Aypak, A. (2023). Clinicopathological profile of peritoneal tuberculosis and a new scoring model for predicting mortality: an international ID-IRI study. European Journal of Clinical Microbiology and Infectious Diseases, 42(8), 981–992. https://doi.org/10.1007/s10096-023-04630-9
BibTeX
@article{tanoglu2023-225123,
author = {Tanoglu, Alpaslan and Erdem, Hakan and Friedland, Jon S. and Ankaralı, Handan and Garcia-Goez, Jose Fernando and Albayrak, Ayşe and El-Kholy, Amani and Ceviker, Sevil Alkan and Amer, Fatma and Erol, Serpil and Darazam, Ilad Alavi and Rabiei, Mohammad Mahdi and Sarwar, Muhammad Zeeshan and Zeb, Misbah and Nawaz, Hassan and Ceylan, Mehmet Resat and Cernat, Roxana and Tasbakan, Meltem and Ayoade, Folusakin and Ruch, Yvon and Tigen, Elif Tükenmez and Angioni, Goffredo and Rajani, Dhanji P. and Akhtar, Nasim and Surme, Serkan and Sengoz, Gonul and Karlıdag, Gulden Eser and Marino, Andrea and Ripon, Rezaul Karim and Çağ, Yasemin and Aydın, Özlem and Akkoyunlu, Yasemin and Seyman, Derya and Angamuthu, Kumar and Cascio, Antonio and Popescu, Corneliu Petru and Sirmatel, Fatma and Eren, Esma and Dar, Razi Even and Munu, Foday Usman and Tanoglu, Esra Guzel and Echeverry, Esteban and Velez, Juan Diego and Artuk, Cumhur and Balin, Safak Ozer and Pandya, Nirav and Erdem, Aysegul and Demiray, Emine Kübra Dindar and Aypak, Adalet},
title = {Clinicopathological profile of peritoneal tuberculosis and a new scoring model for predicting mortality: an international ID-IRI study},
journal = {European Journal of Clinical Microbiology and Infectious Diseases},
year = {2023},
volume = {42},
number = {8},
pages = {981--992},
issn = {0934-9723},
doi = {10.1007/s10096-023-04630-9},
url = {https://akademik.atauni.edu.tr/yayinlar/225123-clinicopathological-profile-of-peritoneal-tuberculosis-and-a-new-scoring-model}
}