Determination of Lidocaine HCl in commercially cream and injection forms by GC-FID method
Özet
In the present study, GC-FID method for the determination of lidocaine HCl in commercially creams and injection forms was developed and validated. The linearity of method was observed in the concentration range of 0.1-5.0 µg/mL. The accuracy (RE%) and precision (RSD%) values of the within-day and between-day of GC-FID method are less than 10.0% and 3.0%, respectively, and also limit of detection (LOD) and the limit of quantitation (LOQ) values were observed as 0.03 and 0.11 µg/mL, respectively. The analytical recovery value of lidocaine HCl was determined as 99.47% on average. As a result, it was concluded that the developed and validated GCFID method can be easily used in routine analyzes in quality control laboratories.
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Atila, A., & Kadıoğlu, Y. (2022). Determination of Lidocaine HCl in commercially cream and injection forms by GC-FID method. Biorganic and Medicinal Chemistry Reports, 5(1), 9–19. https://doi.org/10.25135/bmcr.27.2204.2418
BibTeX
@article{atila2022-22441,
author = {Atila, Alptuğ and Kadıoğlu, Yücel},
title = {Determination of Lidocaine HCl in commercially cream and injection forms by GC-FID method},
journal = {Biorganic and Medicinal Chemistry Reports},
year = {2022},
volume = {5},
number = {1},
pages = {9--19},
issn = {2667-6028},
doi = {10.25135/bmcr.27.2204.2418},
url = {https://akademik.atauni.edu.tr/yayinlar/22441-determination-of-lidocaine-hcl-in-commercially-cream-and-injection-forms-by-gc}
}