Roles of Ki-67, p53, transforming growth factor-beta and lysyl oxidase in the metastasis of lung cancer

Araz, Ömer; Demirci, Elif; Yılmazel Uçar, Elif; Calik, Muhammet; Karaman, Adem; DURUR SUBAŞI, IRMAK; Orsal, Ebru; Subasi, Mahmut; Daloglu, Ferah; AKGÜN, Metin

doi:10.1111/resp.12345

Makale Tam Makale Uluslararası 2014

Roles of Ki-67, p53, transforming growth factor-beta and lysyl oxidase in the metastasis of lung cancer

Ömer Araz, Elif Demirci, Elif Yılmazel Uçar, Muhammet Calik, Adem Karaman, IRMAK DURUR SUBAŞI, Ebru Orsal, Mahmut Subasi, Ferah Daloglu, Metin AKGÜN

RESPIROLOGY Cilt 19 · Sayı 7 · ss. 1034–1039 · 01.10.2014

DOI ile aç

Özet

Background and objectiveMost lung cancer (LC) patients have metastatic disease at time of diagnosis, which influence the treatment regimen and is the most important prognostic factor. The main purpose of our study was to evaluate the relationship between cell proliferation (Ki-67 label index), p53, transforming growth factor- (TGF-) and lysyl oxidase (LOX), and the metastatic stages of different lung cancers. The secondary aim was to correlate these parameters with the standardized uptake value (SUVmax) of the primary lesion during positron emission tomography-computed tomography (PET-CT).

Anahtar kelimeler

SURVIVAL EXPRESSION P53 LUNG-CANCER TGF-beta STAGE Positron-emission tomography adenocarcinoma Ki-67 PROGNOSTIC-SIGNIFICANCE lysyl oxidase POOR-PROGNOSIS

Sürdürülebilir Kalkınma Amaçları

SKA 3: Sağlıklı Bireyler

Atıf için künye

Araz, Ö., Demirci, E., Yılmazel Uçar, E., Calik, M., Karaman, A., DURUR SUBAŞI, I., Orsal, E., Subasi, M., Daloglu, F., & AKGÜN, M. (2014). Roles of Ki-67, p53, transforming growth factor-beta and lysyl oxidase in the metastasis of lung cancer. RESPIROLOGY, 19(7), 1034–1039. https://doi.org/10.1111/resp.12345

BibTeX

@article{araz2014-219516,
  author = {Araz, Ömer and Demirci, Elif and Yılmazel Uçar, Elif and Calik, Muhammet and Karaman, Adem and DURUR SUBAŞI, IRMAK and Orsal, Ebru and Subasi, Mahmut and Daloglu, Ferah and AKGÜN, Metin},
  title = {Roles of Ki-67, p53, transforming growth factor-beta and lysyl oxidase in the metastasis of lung cancer},
  journal = {RESPIROLOGY},
  year = {2014},
  volume = {19},
  number = {7},
  pages = {1034--1039},
  issn = {1323-7799},
  doi = {10.1111/resp.12345},
  url = {https://akademik.atauni.edu.tr/yayinlar/219516-roles-of-ki-67-p53-transforming-growth-factor-beta-and-lysyl-oxidase-in-the}
}