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2015 - AI - CASE REPORT - ENG - ABSTRACT - Intraoral malignant melanoma: an illus-trative report of two case.

Mustafa Doğan, Betül Gündoğdu, Havva Erdem, Handan Bilen, Nesrin Gürsan, Onur Ceylan

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Cilt 119 · Sayı 3 · ss. 207 · 01.03.2015
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Özet

Melanomas develop from melanocytes which are derived from the neural crest. Primary oral mucosal melanoma is rare, accounts for 0.5% of all oral cancers. Oral subtype has the worst prognosis compared to other mucosal melanoma. We report an unusual case of oral mucosal melanoma of the gingiva with the main characteristics of an in situ and invasive lesion.

Case1: The 3 mm incisional gingival biopsy was taken from a 23 year-old man. A presumptive clinical diagnosis of odontogenic cyst was made.

Case2: The excisional gingival biopsy was taken from a 42 year-old man.The biopsy was 2,5 x 2cm in diameter and 2 mm elevated from mucosal surface. The histological examination showed a downward streaming and pigmentation in the dermis of the tumor cells. Immunohistochemical studies showed positivity for HMB 45, Melan-A, S-100 marker.

Conclusion: Oral cavity should be examined. A detailed physical examination reveales a malign tumor in the oral cavity.

Sürdürülebilir Kalkınma Amaçları

  • SKA 3: Sağlıklı Bireyler

Atıf için künye

Doğan, M., Gündoğdu, B., Erdem, H., Bilen, H., Gürsan, N., & Ceylan, O. (2015). 2015 - AI - CASE REPORT - ENG - ABSTRACT - Intraoral malignant melanoma: an illus-trative report of two case. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 119(3), 207. https://doi.org/10.1016/j.oooo.2014.07.465

BibTeX 
@article{dogan2015-219199,
  author = {Doğan, Mustafa and Gündoğdu, Betül and Erdem, Havva and Bilen, Handan and Gürsan, Nesrin and Ceylan, Onur},
  title = {2015 - AI - CASE REPORT - ENG - ABSTRACT - Intraoral malignant melanoma: an illus-trative report of two case.},
  journal = {Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology},
  year = {2015},
  volume = {119},
  number = {3},
  pages = {207},
  issn = {2212-4403},
  doi = {10.1016/j.oooo.2014.07.465},
  url = {https://akademik.atauni.edu.tr/yayinlar/219199-2015-ai-case-report-eng-abstract-intraoral-malignant-melanoma-an-illus-trative}
}