Levosimendan ameliorates cisplatin-induced ototoxicity: Rat model
Özet
Objectives: Cisplatin is employed for chemotherapeutic purposes in several types of adult and pediatric cancer. However, side-effects including nephrotoxicity, ototoxicity, gastrointestinal effects and neuropathy restrict the use of the drug due to their adverse impacts on quality of life. This study aimed to determine whether levosimendan exhibits a protective effect against cisplatin-related ototoxicity in a rat model by means of functional, biochemical and histochemical analysis.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
GÖZELER, M. S., AKDEMİR, F. N. E., Yıldırım, S., Şahin, A., Eser, G., & Aşkın, S. (2019). Levosimendan ameliorates cisplatin-induced ototoxicity: Rat model. International Journal of Pediatric Otorhinolaryngology, 122, 70–75. https://doi.org/10.1016/j.ijporl.2019.04.004
BibTeX
@article{gozeler2019-217380,
author = {GÖZELER, Mustafa Sıtkı and AKDEMİR, FAZİLE NUR EKİNCİ and Yıldırım, Serkan and Şahin, Abdulkadir and Eser, Gizem and Aşkın, Seda},
title = {Levosimendan ameliorates cisplatin-induced ototoxicity: Rat model},
journal = {International Journal of Pediatric Otorhinolaryngology},
year = {2019},
volume = {122},
pages = {70--75},
issn = {0165-5876},
doi = {10.1016/j.ijporl.2019.04.004},
url = {https://akademik.atauni.edu.tr/yayinlar/217380-levosimendan-ameliorates-cisplatin-induced-ototoxicity-rat-model}
}