Makale
Tam Makale
Uluslararası
2020
Characterization and comparison of deferasirox fast disintegrating tablets prepared by direct compression and lyophilization methods
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
Cilt 57 · 01.06.2020
Özet
Objectives: The aim of this study was to develop direct compressed and lyophilized fast disintegrating/dissolving tablets (FDTs) that enhanced disintegration and dissolution of deferasirox, a drug with poor solubility and bioavailability. Although there are conventional oral tablets and tablets for oral suspension of deferasirox in the market, deferasirox oral FDTs are not yet available in the market and under investigation.
Anahtar kelimeler
PERMEABILITY
ABSORPTION
FORMULATION
DIRECT COMPRESSION
lyophilization
Fast disintegrating tablets
Deferasirox
IN-VITRO PERMEABILITY
FORMS
Atıf için künye
Akdag, Y., Gulsun, T., İZAT, N., Çetin, M., ÖNER, L., & ŞAHİN, S. (2020). Characterization and comparison of deferasirox fast disintegrating tablets prepared by direct compression and lyophilization methods. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 57. https://doi.org/10.1016/j.jddst.2020.101760
BibTeX
@article{akdag2020-21535,
author = {Akdag, Yagmur and Gulsun, Tugba and İZAT, NİHAN and Çetin, Meltem and ÖNER, LEVENT and ŞAHİN, SELMA},
title = {Characterization and comparison of deferasirox fast disintegrating tablets prepared by direct compression and lyophilization methods},
journal = {JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY},
year = {2020},
volume = {57},
issn = {1773-2247},
doi = {10.1016/j.jddst.2020.101760},
url = {https://akademik.atauni.edu.tr/yayinlar/21535-characterization-and-comparison-of-deferasirox-fast-disintegrating-tablets}
}