Makale
Tam Makale
Uluslararası
2019
The effects Metformin/Irinotecan-loaded PLGA nanoparticles on glutamate re-uptake time and alteration EAAT1 gene expression level in vitro
Nanomedicine Journal
Cilt 6 · Sayı 1 · ss. 35–42 · 01.12.2019
Özet
Objective(s): The present study was designed to evaluate of Metformin/Irinotecan-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles (NPs) effects on glutamate re-uptake time and receptor expression status in both glioblastoma multiforme (GBM) and cortex neuron cultures. The study was performed on glioblastoma cell line and primer cortex neuron.
Anahtar kelimeler
GROWTH
cytotoxicity
Breast cancer
irinotecan
metformin
PLGA
EAAT1
Voltammetry
INDUCED NEUROTOXICITY
GLIOBLASTOMA
CPT-11
Atıf için künye
TAGHIZADEHGHALEHJOUGHI, A., Hacımüftüoğlu, A., Çetin, M., Kaplan, A. B. U., Bütüner, S., Taspinar, N., & Mohammadzadeh, M. (2019). The effects Metformin/Irinotecan-loaded PLGA nanoparticles on glutamate re-uptake time and alteration EAAT1 gene expression level in vitro. Nanomedicine Journal, 6(1), 35–42. https://doi.org/10.22038/nmj.2019.06.005
BibTeX
@article{taghizadehghalehjoughi2019-21518,
author = {TAGHIZADEHGHALEHJOUGHI, ALI and Hacımüftüoğlu, Ahmet and Çetin, Meltem and Kaplan, Afife Busra Ugur and Bütüner, Selcuk and Taspinar, Numan and Mohammadzadeh, Maryam},
title = {The effects Metformin/Irinotecan-loaded PLGA nanoparticles on glutamate re-uptake time and alteration EAAT1 gene expression level in vitro},
journal = {Nanomedicine Journal},
year = {2019},
volume = {6},
number = {1},
pages = {35--42},
issn = {2322-5904},
doi = {10.22038/nmj.2019.06.005},
url = {https://akademik.atauni.edu.tr/yayinlar/21518-the-effects-metforminirinotecan-loaded-plga-nanoparticles-on-glutamate-re-uptake}
}