Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study
Özet
Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4-1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0-2 weeks, 3-4 weeks and 5-6 weeks of the diagnosis (odds ratio (95%CI) 4.1% (3.3-4.8), 3.9% (2.6-5.1) and 3.6% (2.0-5.2), respectively). Surgery performed >= 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5% (0.9-2.1%)). After a >= 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2-8.7) vs. 2.4% (95%CI 1.4-3.4) vs. 1.3% (95%CI 0.6-2.0%), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. Patients with ongoing symptoms >= 7 weeks from diagnosis may benefit from further delay.
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Nepogodiev, D., Simoes, J. F. F., Li, E., Picciochi, M., Glasbey, J. C., Baiocchi, G., Blanco-Colino, R., Chaudhry, D., AlAmeer, E., El-Boghdadly, K., Wuraola, F., Ghosh, D., Gujjuri, R. R., Harrison, E. M., Lule, H., Kaafarani, H., Khosravi, M., Kronberger, I., Leventoglu, S., … Shefer, N. (2021). Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. ANAESTHESIA, 76(6), 748–758. https://doi.org/10.1111/anae.15458
BibTeX
@article{nepogodiev2021-213609,
author = {Nepogodiev, D. and Simoes, Joana F. F. and Li, Elizabeth and Picciochi, Maria and Glasbey, James C. and Baiocchi, Glauco and Blanco-Colino, Ruth and Chaudhry, Daoud and AlAmeer, Ehab and El-Boghdadly, Kariem and Wuraola, Funmilola and Ghosh, Dhruva and Gujjuri, Rohan R. and Harrison, Ewen M. and Lule, Herman and Kaafarani, Haytham and Khosravi, Mohammad and Kronberger, Irmgard and Leventoglu, Sezai and Mann, Harvinder and Mclean, Kenneth A. and Mengesha, Mengistu Gebreyohanes and Marta Modolo, Maria and Ntirenganya, Faustin and Norman, Lisa and Outani, Oumaima and Pius, Riinu and Pockney, Peter and Qureshi, Ahmad Uzair and Roslani, April Camilla and Satoi, Sohei and Shaw, Catherine and Bhangu, Aneel and Omar, Omar M. and Ahmed, Waheed-Ul-Rahman and Argus, Leah and Ball, Alasdair and Bywater, Edward P. and Blanco-Colino, Ruth and Brar, Amanpreet and Chaudhry, Daoud and Dawson, Brett E. and Duran, Irani and Elhadi, Muhammed and Glasbey, James C. and Gujjuri, Rohan R. and Jones, Conor S. and Harrison, Ewen M. and Kamarajah, Sivesh K. and Keatley, James M. and Lawday, Samuel and Mann, Harvinder and Marson, Ella J. and Mclean, Kenneth A. and Norman, Lisa and Ots, Riinu and Outani, Oumaima and Picciochi, Maria and Santos, Irene and Shaw, Catherine and Taylor, Elliott H. and Trout, Isobel M. and Varghese, Chris and Venn, Mary L. and Xu, William and Dajti, Irida and Gjata, Arben and Kacimi, Salah Eddine Oussama and Boccalatte, Luis and Cox, Daniel and Pockney, Peter and Townend, Philip and Aigner, Felix and Kronberger, Irmgard Elisabeth and Samadov, Elgun and Alderazi, Amer and Hossain, Kamral and Padmore, Greg and van Ramshorst, Gabrielle and Lawani, Ismail and Cerovac, Anis and Delibegovic, Samir and Baiocchi, Glauco and Ataide Gomes, Gustavo Mendonca and Buarque, Igor Lima and Gohar, Muhammad and Slavchev, Mihail and Nwegbu, Chukwuemeka and Agarwal, Arnav and Brar, Amanpreet and Martin, Janet and Ng-Kamstra, Joshua and Olivos, Maricarmen and Lou, Wenhui and Ren, Dong-Lin and Andres Calvache, Jose and J-Perez Rivera, Carlos and Hadzibegovic, Ana Danic and Kopjar, Tomislav and Mihanovic, Jakov and Aviles Jimenez, Pablo Mijahil and Gouvas, Nikolaos and Klat, Jaroslav and Novysedlak, Rene and Amisi, Nicolas and Christensen, Peter and El-Hussuna, Alaa and Batista, Sylvia and Lincango-Naranjo, Eddy and Emile, Sameh and Arevalo Sandoval, Danilo Alfonso and Dhufera, Hailu and Hailu, Samuel and Mengesha, Mengistu G. and Kauppila, Joonas H. and Arnaud, Alexis P. and Demetrashvili, Zaza and Albertsmeier, Markus and Lederhuber, Hans and Loeffler, Markus W. and Acquah, Daniel Kwesi and Ofori, Bernard and Tabiri, Stephen and Metallidis, Symeon and Tsoulfas, Georgios and Aguilera-Arevalo, Maria-Lorena and Recinos, Gustavo and Mersich, Tamas and Wettstein, Daniel and Ghosh, Dhruva and Kembuan, Gabriele and Milan, Peiman Brouki and Khosravi, Mohammad Hossein and Mozafari, Masoud and Hilmi, Ahmed and Mohan, Helen and Zmora, Oded and Gallo, Gaetano and Pata, Francesco and Pellino, Gianluca and Fujimoto, Yuki and Kuroda, Naoto and Satoi, Sohei and Abou Chaar, Mohamad K. and Ayasra, Faris and Fakhradiyev, Ildar and Hamdun, Intisar Hisham Said and Jin-Young, Jang and Jamal, Mohammad and Karout, Lina and Elhadi, Muhammed and Gulla, Aiste and Rasoaherinomenjanahary, Fanjandrainy and Samison, Luc Herve and Roslani, April Camilla and Duran Sanchez, Iran Irani and Samantha Gonzalez, Diana and Martinez, Laura and Jose Martinez, Maria and Nayen, Alejandra and Ramos-De la Medina, Antonio and Assenza, Marco and Aydın, Yener and Ince, Ilker and Ulaş, Ali Bilal and Motas, Natalia and Sedlak, Marian and Kazan, Huseyin Ozgur and Yildirim, Asif and Gulcek, Emre and Drozdov, Evgeniy and Koshel, Andrey and Shefer, Nikolay},
title = {Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study},
journal = {ANAESTHESIA},
year = {2021},
volume = {76},
number = {6},
pages = {748--758},
issn = {0003-2409},
doi = {10.1111/anae.15458},
url = {https://akademik.atauni.edu.tr/yayinlar/213609-timing-of-surgery-following-sars-cov-2-infection-an-international-prospective}
}