Atatürk Üniversitesi Atatürk Üniversitesi
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Makale Tam Makale Uluslararası 2015

The efficacy of spironolactone and surfactant treatment on HMGB1, CRP, IL-1 beta and TNF-alpha levels in acute lung injury

Muhammet Emin Naldan, Conan Atalay, Aysenur Coskun, Muhammet Karaca, Yener Aydın, Emrullah Dorman, Ferah Daloglu, Hüsnü Kürşad, Ömer Araz

Turkish Journal of Thoracic and Cardiovascular Surgery Cilt 23 · Sayı 3 · ss. 538–543 · 01.07.2015
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Özet

Background: This study aims to compare high-mobility group box-1 (HMGB1), interleukin-1 beta (IL-1 beta), tumor necrosis factor alpha (TNF-alpha), and C reactive protein (CRP) levels with spironolactone and surfactant treatment, investigate if spironolactone and surfactant treatment is effective, and evaluate the effect of this treatment on histopathologic changes in the lungs in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS).

Atıf için künye

Naldan, M. E., Atalay, C., Coskun, A., Karaca, M., Aydın, Y., Dorman, E., Daloglu, F., Kürşad, H., & Araz, Ö. (2015). The efficacy of spironolactone and surfactant treatment on HMGB1, CRP, IL-1 beta and TNF-alpha levels in acute lung injury. Turkish Journal of Thoracic and Cardiovascular Surgery, 23(3), 538–543. https://doi.org/10.5606/tgkdc.dergisi.2015.10395

BibTeX
@article{naldan2015-211430,
  author = {Naldan, Muhammet Emin and Atalay, Conan and Coskun, Aysenur and Karaca, Muhammet and Aydın, Yener and Dorman, Emrullah and Daloglu, Ferah and Kürşad, Hüsnü and Araz, Ömer},
  title = {The efficacy of spironolactone and surfactant treatment on HMGB1, CRP, IL-1 beta and TNF-alpha levels in acute lung injury},
  journal = {Turkish Journal of Thoracic and Cardiovascular Surgery},
  year = {2015},
  volume = {23},
  number = {3},
  pages = {538--543},
  issn = {1301-5680},
  doi = {10.5606/tgkdc.dergisi.2015.10395},
  url = {https://akademik.atauni.edu.tr/yayinlar/211430-the-efficacy-of-spironolactone-and-surfactant-treatment-on-hmgb1-crp-il-1-beta}
}