Simultaneous determination of arbutin and its decomposed product hydroquinone in whitening creams using high-performance liquid chromatography with photodiode array detection: Effect of temperature and pH on decomposition

Jeon, J. S.; Kim, B. H.; Lee, S. H.; Kwon, H. J.; Bae, H. J.; Kim, S. K.; Park, J. A.; Shim, J. H.; Hassıbelnaby, Abdelaty Mostafa Abdelaty; Shin, H. C.

doi:10.1111/ics.12228

Makale Tam Makale Uluslararası 2015

Simultaneous determination of arbutin and its decomposed product hydroquinone in whitening creams using high-performance liquid chromatography with photodiode array detection: Effect of temperature and pH on decomposition

J. S. Jeon, B. H. Kim, S. H. Lee, H. J. Kwon, H. J. Bae, S. K. Kim, J. A. Park, J. H. Shim, Abdelaty Mostafa Abdelaty Hassıbelnaby, H. C. Shin

INTERNATIONAL JOURNAL OF COSMETIC SCIENCE Cilt 37 · Sayı 6 · ss. 567–573 · 01.12.2015

DOI ile aç

Özet

OBJECTIVE: Arbutin is an effective agent for the treatment of melanin disorders. Arbutin may be converted to hydroquinone under conditions of high temperature, ultraviolet (UV) radiation and dilute acid. The aim of the current study was to develop an analytical method to determine the levels of arbutin and hydroquinone in whitening cosmetic products using high-performance liquid chromatography with photodiode array detection (HPLC-DAD). In addition, we investigated the effects of high temperature and pH on the decomposition of arbutin.

Anahtar kelimeler

VALIDATION AGENTS SAFETY Temperature HPLC Arbutin hydroquinone high-performance liquid chromatography ETHERS whitening cosmetics COSMETIC PRODUCTS SPECTROMETRIC METHOD KOJIC ACID PHOTOSTABILITY

Atıf için künye

Jeon, J. S., Kim, B. H., Lee, S. H., Kwon, H. J., Bae, H. J., Kim, S. K., Park, J. A., Shim, J. H., Hassıbelnaby, A. M. A., & Shin, H. C. (2015). Simultaneous determination of arbutin and its decomposed product hydroquinone in whitening creams using high-performance liquid chromatography with photodiode array detection: Effect of temperature and pH on decomposition. INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, 37(6), 567–573. https://doi.org/10.1111/ics.12228

BibTeX

@article{jeon2015-209923,
  author = {Jeon, J. S. and Kim, B. H. and Lee, S. H. and Kwon, H. J. and Bae, H. J. and Kim, S. K. and Park, J. A. and Shim, J. H. and Hassıbelnaby, Abdelaty Mostafa Abdelaty and Shin, H. C.},
  title = {Simultaneous determination of arbutin and its decomposed product hydroquinone in whitening creams using high-performance liquid chromatography with photodiode array detection: Effect of temperature and pH on decomposition},
  journal = {INTERNATIONAL JOURNAL OF COSMETIC SCIENCE},
  year = {2015},
  volume = {37},
  number = {6},
  pages = {567--573},
  issn = {0142-5463},
  doi = {10.1111/ics.12228},
  url = {https://akademik.atauni.edu.tr/yayinlar/209923-simultaneous-determination-of-arbutin-and-its-decomposed-product-hydroquinone-in}
}