Advances of functional nucleic acids based on specific recognition:A review
Özet
Nucleic acids, which are fundamental to living organisms, play a crucial role in carrying and transmitting genetic information. Advances in molecular biology have led to the exploration of functional nucleic acids (FNAs), including aptamers, DNAzymes, and G-quadruplexes, known for specific recognition or catalysis. FNAs with high specificity, sequence programmability, modification ease and biocompatibility, have extensive applications in biosensing, environmental monitoring, drug delivery and cancer diagnosis. This review focuses on the structure and specific recognition principles of FNAs, followed by an exploration for biosensing and biomedical applications, offering insights into current challenges and future trends in FNAs as recognition elements.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Liu, B., Chen, G., Hassıbelnaby, A. M. A., Zhai, R., Liu, G., Xu, X., Zhang, Y., Li, L., Zhang, J., & Xu, D. (2025). Advances of functional nucleic acids based on specific recognition:A review. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 304, 140828. https://doi.org/10.1016/j.ijbiomac.2025.140828
BibTeX
@article{liu2025-209810,
author = {Liu, Beibei and Chen, Ge and Hassıbelnaby, Abdelaty Mostafa Abdelaty and Zhai, Rongqi and Liu, Guangyang and Xu, Xiaomin and Zhang, Yanguo and Li, Lingyun and Zhang, Jie and Xu, Donghui},
title = {Advances of functional nucleic acids based on specific recognition:A review},
journal = {INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES},
year = {2025},
volume = {304},
issn = {0141-8130},
doi = {10.1016/j.ijbiomac.2025.140828},
url = {https://akademik.atauni.edu.tr/yayinlar/209810-advances-of-functional-nucleic-acids-based-on-specific-recognitiona-review}
}