An Overview on the Mechanisms and Applications of Enzyme Inhibition-Based Methods for Determination of Organophosphate and Carbamate Pesticides
Özet
Copyright © 2020 American Chemical Society.Acetylcholinesterase inactivating compounds, such as organophosphate (OP) and carbamate (CM) pesticides, are widely used in agriculture to ensure sustainable production of food and feed. As a consequence of their applications, they would result in neurotoxicity, even death. In this essence, the development of enzyme inhibition methods still shows great significance as rapid detection techniques for on-site large-scale screening of OPs and CMs. Initially, mechanisms and applications of various enzyme-inhibition-based methods and devices, including optical colorimetric assay, fluorometric assays, electrochemical biosensors, rapid test card, and microfluidic device, are highlighted in the present overview. Further, to enhance the enzyme sensitivity for detection; alternative enzyme sources or high yield enrichment methods (such as abzyme, artificial enzyme, and recombinant enzyme), as well as enzyme reactivation and identification, are also addressed in this comprehensive overview.
Anahtar kelimeler
Sürdürülebilir Kalkınma Amaçları
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SKA 12: Sorumlu Üretim ve Tüketim
Atıf için künye
Cao, J., Wang, M., Yu, H., She, Y., Cao, Z., Ye, J., Hassıbelnaby, A. M. A., Hacımüftüoğlu, A., Wang, J., & Lao, S. (2020). An Overview on the Mechanisms and Applications of Enzyme Inhibition-Based Methods for Determination of Organophosphate and Carbamate Pesticides. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(28), 7298–7315. https://doi.org/10.1021/acs.jafc.0c01962
BibTeX
@article{cao2020-209731,
author = {Cao, Jing and Wang, Miao and Yu, He and She, Yongxin and Cao, Zhen and Ye, Jiaming and Hassıbelnaby, Abdelaty Mostafa Abdelaty and Hacımüftüoğlu, Ahmet and Wang, Jing and Lao, Shuibing},
title = {An Overview on the Mechanisms and Applications of Enzyme Inhibition-Based Methods for Determination of Organophosphate and Carbamate Pesticides},
journal = {JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY},
year = {2020},
volume = {68},
number = {28},
pages = {7298--7315},
issn = {0021-8561},
doi = {10.1021/acs.jafc.0c01962},
url = {https://akademik.atauni.edu.tr/yayinlar/209731-an-overview-on-the-mechanisms-and-applications-of-enzyme-inhibition-based}
}