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Makale Derleme Uluslararası 2020

COVID-19 Disease and Vitamin D: A Mini-Review

Mohamed Said Boulkrane, Victoria Ilina, Roman Melchakov, Julia Fedotova, Filippo Drago, Lucia Gozzo, Undurti Narasimha Das, Abdelaty Mostafa Abdelaty Hassıbelnaby, Denis Baranenko

FRONTIERS IN PHARMACOLOGY Cilt 11 · 17.12.2020
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Özet

© Copyright © 2020 Boulkrane, Ilina, Melchakov, Fedotova, Drago, Gozzo, Das, Abd El-Aty and Baranenko.Novel coronavirus disease (COVID-19) pandemic caused by SARS-CoV-2, for which there is no effective treatment except employing prevention strategies, has already instituted significant number of deaths. In this review, we provide a scientific view on the potential role of vitamin D in SARS-CoV-2 virus/COVID-19 disease. Vitamin D is well-known to play a significant role in maintaining the immune health of an individual. Moreover, it induces antimicrobial peptide expression that can decrease viral replication and regulate the levels of pro-inflammatory/anti-inflammatory cytokines. Therefore, supplementation of vitamin D has the potential to reduce the incidence, severity and the risk of death from pneumonia resulting from the cytokine storm of many viral infections including COVID-19. We suggest that supplementation of subjects at high risk of COVID-19 with vitamin D (1.000 to 3.000 IU) to maintain its optimum serum concentrations may be of significant benefit for both in the prevention and treatment of the COVID-19.

Anahtar kelimeler

COVID-19 SARS-CoV-2 vitamin D3 respiratory tract infection vitamin D3 receptor

Sürdürülebilir Kalkınma Amaçları

  • SKA 3: Sağlıklı Bireyler

Atıf için künye

Boulkrane, M. S., Ilina, V., Melchakov, R., Fedotova, J., Drago, F., Gozzo, L., Das, U. N., Hassıbelnaby, A. M. A., & Baranenko, D. (2020). COVID-19 Disease and Vitamin D: A Mini-Review. FRONTIERS IN PHARMACOLOGY, 11. https://doi.org/10.3389/fphar.2020.604579

BibTeX 
@article{boulkrane2020-209672,
  author = {Boulkrane, Mohamed Said and Ilina, Victoria and Melchakov, Roman and Fedotova, Julia and Drago, Filippo and Gozzo, Lucia and Das, Undurti Narasimha and Hassıbelnaby, Abdelaty Mostafa Abdelaty and Baranenko, Denis},
  title = {COVID-19 Disease and Vitamin D: A Mini-Review},
  journal = {FRONTIERS IN PHARMACOLOGY},
  year = {2020},
  volume = {11},
  issn = {1663-9812},
  doi = {10.3389/fphar.2020.604579},
  url = {https://akademik.atauni.edu.tr/yayinlar/209672-covid-19-disease-and-vitamin-d-a-mini-review}
}