Magnetic molecularly imprinted polymers doped with graphene oxide for the selective recognition and extraction of four flavonoids from Rhododendron species

Ma, Xingbin; Lin, Hongling; He, Yahui; She, Yongxin; Wang, Miao; Hassıbelnaby, Abdelaty Mostafa Abdelaty; Afifi, Nehal A.; Han, Jianchen; Zhou, Xuzheng; Wang, Jing; Zhang, Jiyu

doi:10.1016/j.chroma.2019.03.053

Makale Tam Makale Uluslararası 2019

Magnetic molecularly imprinted polymers doped with graphene oxide for the selective recognition and extraction of four flavonoids from Rhododendron species

Xingbin Ma, Hongling Lin, Yahui He, Yongxin She, Miao Wang, Abdelaty Mostafa Abdelaty Hassıbelnaby, Nehal A. Afifi, Jianchen Han, Xuzheng Zhou, Jing Wang, Jiyu Zhang

JOURNAL OF CHROMATOGRAPHY A Cilt 1598 · ss. 39–48 · 02.08.2019

DOI ile aç

Özet

© 2019 Elsevier B.V.Herein, a novel magnetic molecularly imprinted polymer doped with reticular graphene oxide (Fe3O4@SiO2-GO@MIPs) was synthesized for the selective recognition and extraction of 4 flavonoids (farrerol, taxifolin, kaempferol, and hyperin) from Rhododendrons species. The Fe3O4@SiO2-GO@MIPs with lamellar membranes showed outstanding adsorption capacity. The 3D cavities complementary to the “shape” of farrerol were “imprinted” on the polymer framework after removal of farrerol template. Competitive binding assays showed that the polymer has a higher selectivity for farrerol compared with other analogues and references. The Fe3O4@SiO2-GO@MIPs as solid-phase extraction adsorbents combined with liquid chromatography-tandem quadrupole mass spectrometry (LC–MS/MS) was used for selective determination of four flavonoids from Rhododendrons samples. The limits of detection (LOD) were 0.07, 0.08, 0.06, and 0.08 μg L−1 for farrerol, taxifolin, kaempferol, and hyperin, respectively. These results suggest that the prepared Fe3O4@SiO2-GO@MIPs have the potential applicability to extract, purify, and enrich flavonoids from herbs, supplements, and other natural products.

Anahtar kelimeler

ALKALOIDS L. PURIFICATION nanoparticles SOLID-PHASE EXTRACTION adsorption GRAPHENE OXIDE PRECONCENTRATION fluoroquinolones SENSITIVE DETERMINATION Farrerol Magnetic extraction and purification Surface molecular imprinting CAPILLARY-ELECTROPHORESIS

Atıf için künye

Ma, X., Lin, H., He, Y., She, Y., Wang, M., Hassıbelnaby, A. M. A., Afifi, N. A., Han, J., Zhou, X., Wang, J., & Zhang, J. (2019). Magnetic molecularly imprinted polymers doped with graphene oxide for the selective recognition and extraction of four flavonoids from Rhododendron species. JOURNAL OF CHROMATOGRAPHY A, 1598, 39–48. https://doi.org/10.1016/j.chroma.2019.03.053

BibTeX

@article{ma2019-209463,
  author = {Ma, Xingbin and Lin, Hongling and He, Yahui and She, Yongxin and Wang, Miao and Hassıbelnaby, Abdelaty Mostafa Abdelaty and Afifi, Nehal A. and Han, Jianchen and Zhou, Xuzheng and Wang, Jing and Zhang, Jiyu},
  title = {Magnetic molecularly imprinted polymers doped with graphene oxide for the selective recognition and extraction of four flavonoids from Rhododendron species},
  journal = {JOURNAL OF CHROMATOGRAPHY A},
  year = {2019},
  volume = {1598},
  pages = {39--48},
  issn = {0021-9673},
  doi = {10.1016/j.chroma.2019.03.053},
  url = {https://akademik.atauni.edu.tr/yayinlar/209463-magnetic-molecularly-imprinted-polymers-doped-with-graphene-oxide-for-the}
}