The Nanosuspension Formulations of Daidzein: Preparation and In Vitro Characterization

Uğur Kaplan, Afife Büşra; ÖZTÜRK, NAİLE; ÇETİN, Meltem; VURAL, İMRAN; Öznülüer Özer, Tuba

doi:10.4274/tjps.galenos.2021.81905

Makale Tam Makale Uluslararası 2022

The Nanosuspension Formulations of Daidzein: Preparation and In Vitro Characterization

Afife Büşra Uğur Kaplan, NAİLE ÖZTÜRK, Meltem ÇETİN, İMRAN VURAL, Tuba Öznülüer Özer

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES Cilt 19 · Sayı 1 · ss. 84–92 · 01.02.2022

DOI ile aç

Özet

Objectives: Daidzein (DZ), a water-insoluble isoflavone, has many beneficial effects (anti-inflammatory, antioxidant, and anticancer effects, etc.) on human health. DZ has a very low oral bioavailability related to its physicochemical properties (low solubility, intense metabolism of DZ in the intestine and liver). This study aimed to prepare and in vitro characterize the nanosuspension formulations of DZ to improve the poor solubility and efficacy of DZ.

Anahtar kelimeler

cytotoxicity nanosuspension daidzein FTIR analysis media milling

Sürdürülebilir Kalkınma Amaçları

SKA 3: Sağlıklı Bireyler

Atıf için künye

Uğur Kaplan, A. B., ÖZTÜRK, N., ÇETİN, M., VURAL, İ., & Öznülüer Özer, T. (2022). The Nanosuspension Formulations of Daidzein: Preparation and In Vitro Characterization. TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, 19(1), 84–92. https://doi.org/10.4274/tjps.galenos.2021.81905

BibTeX

@article{ugurkaplan2022-20650,
  author = {Uğur Kaplan, Afife Büşra and ÖZTÜRK, NAİLE and ÇETİN, Meltem and VURAL, İMRAN and Öznülüer Özer, Tuba},
  title = {The Nanosuspension Formulations of Daidzein: Preparation and In Vitro Characterization},
  journal = {TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES},
  year = {2022},
  volume = {19},
  number = {1},
  pages = {84--92},
  issn = {1304-530X},
  doi = {10.4274/tjps.galenos.2021.81905},
  url = {https://akademik.atauni.edu.tr/yayinlar/20650-the-nanosuspension-formulations-of-daidzein-preparation-and-in-vitro}
}