Memory-vitalizing effect of twenty-five medicinal and edible plants and their isolated compounds

Senol, F. Sezer; Orhan, Ilkay Erdogan; ÖZGEN, UFUK; RENDA, GÜLİN; BULUT, Gokhan; Güven, Leyla; Sezen Karaoğlan, Esen; Sevindik, Handan Gökben; Skalicka-Wozniak, Krystyna; Caliskan, Ufuk Koca; Sekeroglu, Nazim

doi:10.1016/j.sajb.2015.07.011

Makale Tam Makale Uluslararası 2016

Memory-vitalizing effect of twenty-five medicinal and edible plants and their isolated compounds

F. Sezer Senol, Ilkay Erdogan Orhan, UFUK ÖZGEN, GÜLİN RENDA, Gokhan BULUT, Leyla Güven, Esen Sezen Karaoğlan, Handan Gökben Sevindik, Krystyna Skalicka-Wozniak, Ufuk Koca Caliskan, Nazim Sekeroglu

SOUTH AFRICAN JOURNAL OF BOTANY Cilt 102 · ss. 102–109 · 01.01.2016

DOI ile aç

Özet

The extracts from 25 plant species from Salvia, Hypericum, Onosma, Thymus, Origanum, Rosa, and Prunus with eight isolated compounds were screened for their memory-vitalizing potential against the enzymes, i.e., acetyl cholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase (TYR) along with DPPH, DMPD, and NO radicals and iron-chelation capacity using spectrophotometric microtiter assays. The n-hexane:dichloromethane (1:1) extract of Onosma nigricaule roots (63.18 +/- 0.56%) and the ethyl acetate extract of the aerial parts of Hypericum capitatum var. capitatum (50.79 +/- 3.88%) were the most active toward AChE and BChE, respectively. The highest iron-chelating capacity was found in the n-hexane extract of Thymus sipyleus subsp. sipyleus var. sipyleus, where mostly Labiatae species exhibited better radical scavenging effect. Among the extracts, the roots of O. nigricaule, the aerial parts of Hypericum capitatum var. capitatum and T. sipyleus subsp. sipyleus var. sipyleus could be further evaluated for their memory-vitalizing properties based on different mechanisms. (C) 2015 SAAB. Published by Elsevier B.V. All rights reserved.

Anahtar kelimeler

antioxidant anticholinesterase ENZYMES L. Acetylcholinesterase Butyrylcholinesterase enzyme inhibition EXTRACTS EXTRACT CHOLINESTERASE ANTIOXIDANT ACTIVITIES Tyrosinase Screening ST JOHNS WORT

Atıf için künye

Senol, F. S., Orhan, I. E., ÖZGEN, U., RENDA, G., BULUT, G., Güven, L., Sezen Karaoğlan, E., Sevindik, H. G., Skalicka-Wozniak, K., Caliskan, U. K., & Sekeroglu, N. (2016). Memory-vitalizing effect of twenty-five medicinal and edible plants and their isolated compounds. SOUTH AFRICAN JOURNAL OF BOTANY, 102, 102–109. https://doi.org/10.1016/j.sajb.2015.07.011

BibTeX

@article{senol2016-20502,
  author = {Senol, F. Sezer and Orhan, Ilkay Erdogan and ÖZGEN, UFUK and RENDA, GÜLİN and BULUT, Gokhan and Güven, Leyla and Sezen Karaoğlan, Esen and Sevindik, Handan Gökben and Skalicka-Wozniak, Krystyna and Caliskan, Ufuk Koca and Sekeroglu, Nazim},
  title = {Memory-vitalizing effect of twenty-five medicinal and edible plants and their isolated compounds},
  journal = {SOUTH AFRICAN JOURNAL OF BOTANY},
  year = {2016},
  volume = {102},
  pages = {102--109},
  issn = {0254-6299},
  doi = {10.1016/j.sajb.2015.07.011},
  url = {https://akademik.atauni.edu.tr/yayinlar/20502-memory-vitalizing-effect-of-twenty-five-medicinal-and-edible-plants-and-their}
}