In Vitro Assessment of Hemostatic Performances of Salvia verticillata, Achillea biebersteinii, Tragopogon aureus, and Cephalaria procera.
Özet
Hemostasis is an inherent function and natural processes to prevent or stop bleeding. Nowadays
great efforts are being made to develop novel, economic and high-performance products to control
bleeding. In this study, we aimed to assess the in vitro hemostatic effects by four several plant
species used in folk medicine for different purposes including Salvia verticillata, Achillea
biebersteinii, Tragopogon aureus, and Cephalaria procera. The extracts with different solvent
nature were prepared and their hemostatic efficacy were determined using optical aggregometry.
The present results clearly revealed that the extracts of S. verticillata showed the highest efficacy
on platelet aggregation in presence of adenosine-diphosphate (ADP) (80.77%), collagen (80.78%),
and arachidonic acid (AA) (73.71%) when compared to other plant extracts. Again, the most
effective platelet aggregation (47.27%) was determined after application C. procera with in the
presence of epinephrine (EPI). Moreover, we firstly executed that n-butanol and ethyl acetate
extracts led to the highest percantages of platelet aggregation in the presence of APD, collagen,
AA and EPI. In a conclusion, our findings suggested that the tested medicinal plants in particular
S. verticillata and C. procera could be novel and natural sources of effective hemostatic agents.
Atıf için künye
Karakaya, S., ÖZDEMİR TOZLU, Ö., İncekara, Ü., TÜRKEZ, H., & Aksakal, Ö. (2021). In Vitro Assessment of Hemostatic Performances of Salvia verticillata, Achillea biebersteinii, Tragopogon aureus, and Cephalaria procera. 3 rd International Symposium on Biodiversity Research, Erzurum.
BibTeX
@inproceedings{karakaya2021-20287,
author = {Karakaya, Songül and ÖZDEMİR TOZLU, ÖZLEM and İncekara, Ümit and TÜRKEZ, HASAN and Aksakal, Özkan},
title = {In Vitro Assessment of Hemostatic Performances of Salvia verticillata, Achillea biebersteinii, Tragopogon aureus, and Cephalaria procera.},
booktitle = {3 rd International Symposium on Biodiversity Research},
address = {Erzurum},
year = {2021},
url = {https://akademik.atauni.edu.tr/yayinlar/20287-in-vitro-assessment-of-hemostatic-performances-of-salvia-verticillata-achillea}
}