The effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinolhydrochloride (C1), indomethacin, nimesulide and rofecoxib on cyclooxygenase activities in carrageenan-induced paw edema model
Özet
Aim: The aim of this study was to investigate the effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride (C1) which is a structural and also non-classical isomer of bis Mannich base, bis (3-aryl-3-oxo-propyl) methylamine hydrochlorides (B1), on cyclooxygenase (COX) activities in 48 rats with inflammation by using carrageenan-induced paw edema, and to compare its effect with other non-steroidal anti-inflammatory drugs (NSAIDs).
Atıf için künye
ŞAHİN, Y. N., Demircan, B., SÜLEYMAN, H., AKSOY, H., & Gül, H. İ. (2010). The effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinolhydrochloride (C1), indomethacin, nimesulide and rofecoxib on cyclooxygenase activities in carrageenan-induced paw edema model. TURKISH JOURNAL OF MEDICAL SCIENCES, 40(5), 723–728. https://doi.org/10.3906/sag-0908-187
BibTeX
@article{sahin2010-19958,
author = {ŞAHİN, Yaşar Nuri and Demircan, Berna and SÜLEYMAN, Halis and AKSOY, Hülya and Gül, Halise İnci},
title = {The effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinolhydrochloride (C1), indomethacin, nimesulide and rofecoxib on cyclooxygenase activities in carrageenan-induced paw edema model},
journal = {TURKISH JOURNAL OF MEDICAL SCIENCES},
year = {2010},
volume = {40},
number = {5},
pages = {723--728},
issn = {1300-0144},
doi = {10.3906/sag-0908-187},
url = {https://akademik.atauni.edu.tr/yayinlar/19958-the-effects-of-3-benzoyl-1-methyl-4-phenyl-4-piperidinolhydrochloride-c1}
}