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Makale Tam Makale Uluslararası 2022

Evaluation of anticholinesterase effect of some Epilobium species and quantification of hyperoside by HPLC

Songül Karakaya, İPEK SÜNTAR, BİLGE AYDIN, Benan Dursunoglu, SEFA GÖZCÜ, Onur Şenol, Burak BAYRAK, Hilal Özbek, Mehmet Koca, Songul Ceribasi, Omer Faruk Yakinci, Zühal Güvenalp, Yücel Kadıoğlu

NATURAL PRODUCT RESEARCH Cilt 36 · Sayı 5 · ss. 1296–1299 · 01.01.2022
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Özet

This article presents the evaluation of anticholinesterase effects of aerial parts of Epilobium angustifolium, E. stevenii and E. hirsutum and isolated flavonoids from E. angustifolium, and quantification of the flavonoids by HPLC. Besides, the highest acetylcholinesterase inhibition was seen in the EtOAc sub-extracts of E. angustifolium and E. stevenii (36.51 +/- 1.88 and 39.89 +/- 3.09%, respectively), whereas EtOAc sub-extract of E. angustifolium had the best butyrylcholinesterase inhibition (62.09 +/- 1.98%). Hyperoside showed strong inhibition activity on both enzymes. The active EtOAc sub-extract of E. angustifolium was quantitatively analyzed for their content of hyperoside (quercetin-3-O-beta-D-galactoside) by HPLC. The content of hyperoside in EtOAc sub-extract of E. angustifolium was detected as 3.312%. The anatomical structures of the stem, leaf, sepal, petal, anther, and filament of E. angustifolium were investigated. The anatomical properties given in this study provide a description of E. angustifolium.

Anahtar kelimeler

ANATOMY anticholinesterase Epilobium Hyperoside Onagraceae

Atıf için künye

Karakaya, S., SÜNTAR, İ., AYDIN, B., Dursunoglu, B., GÖZCÜ, S., Şenol, O., BAYRAK, B., Özbek, H., Koca, M., Ceribasi, S., Yakinci, O. F., Güvenalp, Z., & Kadıoğlu, Y. (2022). Evaluation of anticholinesterase effect of some Epilobium species and quantification of hyperoside by HPLC. NATURAL PRODUCT RESEARCH, 36(5), 1296–1299. https://doi.org/10.1080/14786419.2020.1856841

BibTeX 
@article{karakaya2022-18987,
  author = {Karakaya, Songül and SÜNTAR, İPEK and AYDIN, BİLGE and Dursunoglu, Benan and GÖZCÜ, SEFA and Şenol, Onur and BAYRAK, Burak and Özbek, Hilal and Koca, Mehmet and Ceribasi, Songul and Yakinci, Omer Faruk and Güvenalp, Zühal and Kadıoğlu, Yücel},
  title = {Evaluation of anticholinesterase effect of some Epilobium species and quantification of hyperoside by HPLC},
  journal = {NATURAL PRODUCT RESEARCH},
  year = {2022},
  volume = {36},
  number = {5},
  pages = {1296--1299},
  issn = {1478-6419},
  doi = {10.1080/14786419.2020.1856841},
  url = {https://akademik.atauni.edu.tr/yayinlar/18987-evaluation-of-anticholinesterase-effect-of-some-epilobium-species-and}
}