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Makale Tam Makale Uluslararası 2011

In vitro effects of rosmarinic acid on glutathione reductase and glucose 6-phosphate dehydrogenase

Berivan Tandogan, Ayse Kuruuzum-Uz, Cihangir Sengezer, Zühal Güvenalp, LÜTFİYE ÖMÜR DEMİREZER, N. Nuray Ulusu

Pharmaceutical biology Cilt 49 · Sayı 6 · ss. 587–594 · 01.06.2011
DOI ile aç

Özet

Context: Glutathione reductase (GR, NADPH:oxidized glutathione oxidoreductase, E. C 1.6.4.2) is a flavoprotein that catalyzes the NADPH-dependent reduction of oxidized glutathione (GSSG). GR is a crucial enzyme in the antioxidant system by maintaining reduced glutathione (GSH). Glucose 6-phosphate dehydrogenase (G6PD, glucose 6-phosphate (G6P):NADP(+) oxidoreductase, EC 1.1.1.49) is the key regulatory enzyme of the pentose phosphate pathway and maintains NADPH for reductive reactions.

Anahtar kelimeler

antioxidant kidney α-amylase DERIVATIVES enzyme inhibition PURIFICATION kinetics natural product NATURAL PHENOLIC-COMPOUNDS BINDING MECHANISM SUBSTRATE

Atıf için künye

Tandogan, B., Kuruuzum-Uz, A., Sengezer, C., Güvenalp, Z., DEMİREZER, L. Ö., & Ulusu, N. N. (2011). In vitro effects of rosmarinic acid on glutathione reductase and glucose 6-phosphate dehydrogenase. Pharmaceutical biology, 49(6), 587–594. https://doi.org/10.3109/13880209.2010.533187

BibTeX 
@article{tandogan2011-18983,
  author = {Tandogan, Berivan and Kuruuzum-Uz, Ayse and Sengezer, Cihangir and Güvenalp, Zühal and DEMİREZER, LÜTFİYE ÖMÜR and Ulusu, N. Nuray},
  title = {In vitro effects of rosmarinic acid on glutathione reductase and glucose 6-phosphate dehydrogenase},
  journal = {Pharmaceutical biology},
  year = {2011},
  volume = {49},
  number = {6},
  pages = {587--594},
  issn = {1388-0209},
  doi = {10.3109/13880209.2010.533187},
  url = {https://akademik.atauni.edu.tr/yayinlar/18983-in-vitro-effects-of-rosmarinic-acid-on-glutathione-reductase-and-glucose-6}
}