COMPARISON OF SOME BIOLOGICAL ACTIVITIES AND CATECHIN TANNIN CONTENTS OF TWO JUNIPERUS AND PRUNUS SPECIES İKİ JUNİPERUS VE PRUNUS TÜRÜNÜN BAZI BİYOLOJİK AKTİVİTELERİNİN VE KATEŞİN TANEN İÇERİKLERİNİN KARŞILAŞTIRILMASI
Özet
Objective: Qualitative and quantitative determination of catechin in fruits of J. communis var. saxatilis, J. oxycedrus subsp. oxycedrus, P. spinosa, and P. cerasifera was analyzed by LC-MS/MS using standards. Antidiabetic, antimicrobial, and antioxidant activities of fruit and cone extracts of these plants were evaluated. Qualitative analysis of secondary metabolites was also done. Material and Method: Antimicrobial activity was done with MIC. ABTS·+ and DPPH• scavenging activies were used antioxidant activity. α-Amylase and α-glucosidase inhibition assays were done for antidiabetic activity. Result and Discussion: JCS (IC50 = 578 ± 20 μg/ml), JOO (IC50 = 3706 ± 52 μg/ml), and PS (IC50 = 313 ± 7 μg/ml) extracts were observed to show a higher activity than acarbose (IC50 = 4061 ± 146 μg/ml). J. communis var. saxatilis fruit extract was observed with MIC values between (312.5 - 2500 µg/ml) against all microorganisms. JCS extract has the highest phenolic composition and JOO has the lowest phenolic composition (µg GAE/ mg extract). JCS extract indicated the highest antioxidant activity. It was determined that plant containing the highest catechin (1173.3±5.77 ng/ml) and epigallocatechin (208±7.21 ng/ml) was JCS. In this research, it can be said that JCS with the highest tannin content shows the highest effects.
Anahtar kelimeler
Atıf için künye
Yuca, H., Demi̇Rcan, H. C., AYDIN, B., Önal, M., Tekman, E., Ci̇Vaş, A., Nobari̇Rezaeyeh, M., Göger, G., Karakaya, S., & Güvenalp, Z. (2023). COMPARISON OF SOME BIOLOGICAL ACTIVITIES AND CATECHIN TANNIN CONTENTS OF TWO JUNIPERUS AND PRUNUS SPECIES İKİ JUNİPERUS VE PRUNUS TÜRÜNÜN BAZI BİYOLOJİK AKTİVİTELERİNİN VE KATEŞİN TANEN İÇERİKLERİNİN KARŞILAŞTIRILMASI. Ankara Universitesi Eczacilik Fakultesi Dergisi, 47(2), 650–666. https://doi.org/10.33483/jfpau.1218845
BibTeX
@article{yuca2023-18507,
author = {Yuca, Hafize and Demi̇Rcan, Hakkı Cem and AYDIN, BİLGE and Önal, Mehmet and Tekman, Enes and Ci̇Vaş, Ayşe and Nobari̇Rezaeyeh, Mohaddeseh and Göger, Gamze and Karakaya, Songül and Güvenalp, Zühal},
title = {COMPARISON OF SOME BIOLOGICAL ACTIVITIES AND CATECHIN TANNIN CONTENTS OF TWO JUNIPERUS AND PRUNUS SPECIES İKİ JUNİPERUS VE PRUNUS TÜRÜNÜN BAZI BİYOLOJİK AKTİVİTELERİNİN VE KATEŞİN TANEN İÇERİKLERİNİN KARŞILAŞTIRILMASI},
journal = {Ankara Universitesi Eczacilik Fakultesi Dergisi},
year = {2023},
volume = {47},
number = {2},
pages = {650--666},
issn = {2564-6524},
doi = {10.33483/jfpau.1218845},
url = {https://akademik.atauni.edu.tr/yayinlar/18507-comparison-of-some-biological-activities-and-catechin-tannin-contents-of-two}
}