THE RELATIONSHIP BETWEEN THE SEVERITY OF PERIAPICAL PERIODONTITIS AND MEAN PLATELET VOLUME (MPV) AND OTHER INFLAMMATORY MARKERS IN CHILDREN
Özet
Aim: Delayed treatment of odontogenic infections may amplify the systemic effects of local infections in
children. Studies investigating changes in systemic inflammation markers in children whose dental treatments
are neglected are limited. This study aims to investigate the relationship between the severity of chronic apical
periodontitis and the parameters of mean platelet volume (MPV), previously studied in relation to various
inflammatory diseases, as well as neutrophilic granulocytes (NEUT), lymphocytes (LYMPH), and platelets
(PLT).
Methods: A total of 104 healthy patients with periapical periodontitis, who underwent dental treatment under
general anesthesia (GA) between 01.10.2023 and 01.09.2024, were included in the study. The periapical statuses
were dichotomized as mild and severe. Periapical Index (PAI) scores of 2 or 3 were classified as 'mild,' whereas
scores of 4 or 5 were classified as 'severe.' Complete blood count (CBC) parameters, including NEUT,
LYMPH, PLT, and MPV, were recorded. A significance level of p<0.05 was considered in the study.
Results: Of the 104 patients included, 41 were in the mild periapical periodontitis group and 63 in the severe
group. The average age of the children was 5.4±1.2 years. The results showed no significant differences
between the mild and severe periapical periodontitis groups in terms of LYMPH, PLT, and MPV (p>0.05).
However, the NEUT score in the severe periapical periodontitis group was statistically higher than in the mild
group (p<0.05).
Conclusions: Our study observed that MPV, PLT, and LYMPH biomarkers were not associated with the
severity of apical periodontitis, but the NEUT biomarker was elevated in cases of more severe apical
periodontitis. This study may serve as a pioneering effort in evaluating the systemic effects of odontogenic
infections, which typically manifest as local infections, using CBC parameters. However, more comprehensive,
multi-center studies are recommended
Atıf için künye
Saraç, F. (2024). THE RELATIONSHIP BETWEEN THE SEVERITY OF PERIAPICAL PERIODONTITIS AND MEAN PLATELET VOLUME (MPV) AND OTHER INFLAMMATORY MARKERS IN CHILDREN. 4. International Congress of Contemporary Pediatric Dentistry, Ankara (ss. 23).
BibTeX
@inproceedings{sarac2024-17835,
author = {Saraç, Fatma},
title = {THE RELATIONSHIP BETWEEN THE SEVERITY OF PERIAPICAL PERIODONTITIS AND MEAN PLATELET VOLUME (MPV) AND OTHER INFLAMMATORY MARKERS IN CHILDREN},
booktitle = {4. International Congress of Contemporary Pediatric Dentistry},
address = {Ankara},
year = {2024},
pages = {23},
url = {https://akademik.atauni.edu.tr/yayinlar/17835-the-relationship-between-the-severity-of-periapical-periodontitis-and-mean}
}