Content and composition of fatty acids in normal and inflamed gingival tissues

Cicek, Y; Ozmen, I; Canakci, V; Dilsiz, Alparslan; Sahin, F

doi:10.1016/j.plefa.2004.10.013

Makale Tam Makale Uluslararası 2005 Açık erişimli

Content and composition of fatty acids in normal and inflamed gingival tissues

Y Cicek, I Ozmen, V Canakci, Alparslan Dilsiz, F Sahin

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS Cilt 72 · Sayı 3 · ss. 147–151 · 01.03.2005

DOI ile aç

Özet

The balance of essential fatty acid is important for good health and normal development. Essential fatty acids (EFA) are the precursors of prostaglandins (PGs), thromboxanes and leukotrienes (LT). The aim of this clinical study was to determine the total fatty acid level of polyunsaturated fatty acids (PUFA), monounsaturated fatty acids (MUFA), saturated fatty acids (SFA) and each fatty acids level of inflamed and normal gingival tissues. Twenty-seven subjects were included the present study. Nineteen samples of inflamed human gingival tissue (nine of fibrous hyperplasia (FH), ten of peripheral giant cell granuloma (PGCG) and eight samples of normal human gingival tissue were analyzed. The characteristics of inflammation were assessed histologically. Variance analyses were performed to assess the differences among tissues. The total cellular fatty acid profiles of the tissues in inflamed human gingival tissue and in eight samples of normal human gingival tissue were determined by gas chromatography using Sherlock microbial identification system (MIS) software (Microbial ID, Newark, DE, USA) with a database of FAME profiles for eukary. PUFAs, MUFAs, and SFAs were quantified by Sherlock microbial identification system (MIS) or database gas chromatography (DGC). There were statistically significant differences between the concentrations in inflamed (FH, PGCG) and healthy gingival tissues for PUFA and MUFA (P<0.001, P<0,011, respectively). There were statistically significant differences among the concentrations in FH, PGCG, and healthy gingival tissues for SFA (P<0.0001). Arachidonic acid, docosahexaenoic acid, linoleic acid were increased in inflamed tissue. The results of this study showed that unsaturated fatty acids (PUFA and MUFA) significantly increased in inflamed gingival tissues. (C) 2004 Elsevier Ltd. All rights reserved.

Sürdürülebilir Kalkınma Amaçları

SKA 3: Sağlıklı Bireyler

Atıf için künye

Cicek, Y., Ozmen, I., Canakci, V., Dilsiz, A., & Sahin, F. (2005). Content and composition of fatty acids in normal and inflamed gingival tissues. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 72(3), 147–151. https://doi.org/10.1016/j.plefa.2004.10.013

BibTeX

@article{cicek2005-13687,
  author = {Cicek, Y and Ozmen, I and Canakci, V and Dilsiz, Alparslan and Sahin, F},
  title = {Content and composition of fatty acids in normal and inflamed gingival tissues},
  journal = {PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS},
  year = {2005},
  volume = {72},
  number = {3},
  pages = {147--151},
  issn = {0952-3278},
  doi = {10.1016/j.plefa.2004.10.013},
  url = {https://akademik.atauni.edu.tr/yayinlar/13687-content-and-composition-of-fatty-acids-in-normal-and-inflamed-gingival-tissues}
}