Low-grade tubulopapillary adenocarcinoma of sinonasal tumors: Diagnosis and follow-up

ABSTRACT<o:p></o:p>

Low grade

tubulopapillary adenocarcinoma is one of the rare sinonasal tumors. A

65-year-old male patient was admitted to our clinic with painless intraoral and

extraoral swelling and speech disorder. Radiological examination of

the patient revealed a lesion suggesting malignancy. The area of ​​the lesion

spread from the left maxillary area to the maxillary sinus, nasal cavity,

zygomatic bone and the base of the eye, causing resorption of the bones in the

regions. As a result of biopsy, the lesion was diagnosed as well-differentiated

low-grade tubulopapillary adenocarcinoma. The patient was referred to the

oncology department of the medical faculty and the radiotherapy was started by

the medical faculty board, indicating that it was not suitable for surgical

treatment. After 1.5-year follow-up, the patient was re-biopsied and diagnosed

as poorly differentiated tubulopapillary adenocarcinoma. We think that the

aggressive lesion may show heterogeneous differentiation as a possible reason

for the differentiation between the two biopsies.<o:p></o:p>

Keywords: low grade tubulopapillary adenocarcinoma; sinonasal

tumors; ultrasonography; magnetic resonance imaging