Article 2025 · 1 citations

Synthesis of compounds including cyclopropane ring: Selectivity in additions

Menzek, Abdullah, Sirtbasi, Sedef, Sahin, Ertan, Bayrak, Cetin, Olgun, Mahire E., Yavari, Ali, Bayram, Sefa, Rezaei, Mohsen

Abstract

As a result of reactions such as addition, cis diolization, esterification and bromination, thirteen compounds containing spirocyclopropane were synthesized from spiro[2,4]hepta-4,6-diene (5) as the starting compound. Among these compounds, seven compounds also have an additional cyclopropane ring. A 1,3-Dipolar cycloaddition reaction of the compound obtained from cycloheptatriene-PTAD, an adduct was selectively synthesized. Additionally, bromine was selectively added to the endo-ester, resultingthe reaction of 5 and ethyl diazoacetate. The rearranged product monobromo 12 was obtained from reaction molecular bromine with compound 7 , The structure of its was determined by X-ray diffraction analysis. The structure of some compounds (9, 23 and 24 ) were also determined by X-ray diffraction analysis. Additionally, compound 27 was obtained as endo-selectivity.

Keywords

Bromination Cyclopropane Cycloaddition Spirocyclopentadiene Strained compounds CYCLOADDITION REACTIONS REARRANGEMENT REACTIONS DERIVATIVES BENZONORBORNADIENE

WoS Categories

Chemistry, Physical

Sustainable Development Goals

Good Health and Well-being

Citation

Journal: JOURNAL OF MOLECULAR STRUCTURE
Year: 2025
Volume: 1324
ISSN: 0022-2860
eISSN: 1872-8014
DOI: 10.1016/j.molstruc.2024.140807
WoS UID: WOS:001371471300001

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