Synthesis of compounds including cyclopropane ring: Selectivity in additions
Menzek, Abdullah, Sirtbasi, Sedef, Sahin, Ertan, Bayrak, Cetin, Olgun, Mahire E., Yavari, Ali, Bayram, Sefa, Rezaei, Mohsen
As a result of reactions such as addition, cis diolization, esterification and bromination, thirteen compounds containing spirocyclopropane were synthesized from spiro[2,4]hepta-4,6-diene (5) as the starting compound. Among these compounds, seven compounds also have an additional cyclopropane ring. A 1,3-Dipolar cycloaddition reaction of the compound obtained from cycloheptatriene-PTAD, an adduct was selectively synthesized. Additionally, bromine was selectively added to the endo-ester, resultingthe reaction of 5 and ethyl diazoacetate. The rearranged product monobromo 12 was obtained from reaction molecular bromine with compound 7 , The structure of its was determined by X-ray diffraction analysis. The structure of some compounds (9, 23 and 24 ) were also determined by X-ray diffraction analysis. Additionally, compound 27 was obtained as endo-selectivity.
- Dergi
- JOURNAL OF MOLECULAR STRUCTURE
- Yıl
- 2025
- Cilt
- 1324
- ISSN
- 0022-2860
- eISSN
- 1872-8014
- DOI
- 10.1016/j.molstruc.2024.140807
- WoS UID
- WOS:001371471300001