Article 2024 · 0 citations

Olfactory bulbectomy leads to prolonged induction phase of sevoflurane anesthesia in rats

Ahiskalioglu, Ali, Kanat, Ayhan, Aydin, Mehmet Dumlu, Kazdal, Hizir, Kocak, Nuri, Ozmen, Sevilay

Abstract

The effect of olfactory bulb lesions on the induction time of sevoflurane has never been studied. We aimed to investigate this issue. In this study, we found that the volume of olfactory bulbs and the pore of the fila olfactoria were significantly lower with the fibrosis of olfactory bulbs in animals subjected to olfactory bulbectomy. Volatile anesthetics induction times were measured in all groups. Prolonged induction was observed in olfactory bulbectomy group. It was concluded that increased induction times of sevoflurane may be due to the olfactory bulb lesion.

Keywords

anesthesia fila olfactoria induction time nose-to-brain delivery olfactory bulb olfactory bulbectomy sevoflurane transport pathway volatile anesthetics SUBARACHNOID HEMORRHAGE ISOFLURANE DESFLURANE

WoS Categories

Medicine, Research & Experimental

Sustainable Development Goals

Good Health and Well-being

Citation

Journal: MEDICAL GAS RESEARCH
Year: 2024
Volume: 14
Issue: 1
Pages: 33-37
ISSN: 2045-9912
DOI: 10.4103/2045-9912.378881
WoS UID: WOS:001158358000003

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