Article 2024 · 0 atıf

Olfactory bulbectomy leads to prolonged induction phase of sevoflurane anesthesia in rats

Ahiskalioglu, Ali, Kanat, Ayhan, Aydin, Mehmet Dumlu, Kazdal, Hizir, Kocak, Nuri, Ozmen, Sevilay

Özet

The effect of olfactory bulb lesions on the induction time of sevoflurane has never been studied. We aimed to investigate this issue. In this study, we found that the volume of olfactory bulbs and the pore of the fila olfactoria were significantly lower with the fibrosis of olfactory bulbs in animals subjected to olfactory bulbectomy. Volatile anesthetics induction times were measured in all groups. Prolonged induction was observed in olfactory bulbectomy group. It was concluded that increased induction times of sevoflurane may be due to the olfactory bulb lesion.

Anahtar Kelimeler

anesthesia fila olfactoria induction time nose-to-brain delivery olfactory bulb olfactory bulbectomy sevoflurane transport pathway volatile anesthetics SUBARACHNOID HEMORRHAGE ISOFLURANE DESFLURANE

WoS Kategorileri

Medicine, Research & Experimental

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: MEDICAL GAS RESEARCH
Yıl: 2024
Cilt: 14
Sayı: 1
Sayfa: 33-37
ISSN: 2045-9912
DOI: 10.4103/2045-9912.378881
WoS UID: WOS:001158358000003

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